Ocular Manifestations of West Nile Virus
Ocular manifestations are a feature of West Nile virus infection. They mostly occur in association with severe neuroinvasive disease. Linear chorioretinitis is suggestive of the diagnosis and may raise diagnostic suspicion when associated with evocative systemic signs, and in an epidemic context. Va...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-11-01
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| Series: | Vaccines |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-393X/8/4/641 |
| _version_ | 1827702953241214976 |
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| author | Antoine Rousseau Oscar Haigh Imen Ksiaa Moncef Khairallah Marc Labetoulle |
| author_facet | Antoine Rousseau Oscar Haigh Imen Ksiaa Moncef Khairallah Marc Labetoulle |
| author_sort | Antoine Rousseau |
| collection | DOAJ |
| description | Ocular manifestations are a feature of West Nile virus infection. They mostly occur in association with severe neuroinvasive disease. Linear chorioretinitis is suggestive of the diagnosis and may raise diagnostic suspicion when associated with evocative systemic signs, and in an epidemic context. Various other less specific inflammatory ocular manifestations have been reported, including anterior uveitis, occlusive retinal vasculitis, optic neuritis, and diplopia. The pathophysiology of ocular disease remains unclear, but it reflects the neuroinvasiveness of the disease. Although ocular involvement most often resolves without visual sequelae, some patients may have permanent loss of vision, adding to the need for the development of a specific treatment and/or vaccines. |
| first_indexed | 2024-03-10T15:08:41Z |
| format | Article |
| id | doaj.art-16440e6930ee4eb697dde132d5ee4600 |
| institution | Directory Open Access Journal |
| issn | 2076-393X |
| language | English |
| last_indexed | 2024-03-10T15:08:41Z |
| publishDate | 2020-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Vaccines |
| spelling | doaj.art-16440e6930ee4eb697dde132d5ee46002023-11-20T19:30:39ZengMDPI AGVaccines2076-393X2020-11-018464110.3390/vaccines8040641Ocular Manifestations of West Nile VirusAntoine Rousseau0Oscar Haigh1Imen Ksiaa2Moncef Khairallah3Marc Labetoulle4Department of Ophthalmology, Bicêtre Hospital, Public Assistance, Hospitals of Paris, Reference Network for Rare Diseases in Ophthalmology (OPHTARA), 94270 Le Kremlin-Bicêtre, FranceCenter for Immunology of Viral, Auto-Immune, Hematological and Bacterial Diseases (IMVA-HB), Infectious Diseases Models for Innovative Therapies (IDMIT), French Alternative Energies and Atomic Commission (CEA), 92260 Fontenay-aux-Roses, FranceDepartment of Ophthalmology, Fattouma Bourguiba University Hospital, Faculty of Medicine; Monastir 5019, TunisiaDepartment of Ophthalmology, Fattouma Bourguiba University Hospital, Faculty of Medicine; Monastir 5019, TunisiaDepartment of Ophthalmology, Bicêtre Hospital, Public Assistance, Hospitals of Paris, Reference Network for Rare Diseases in Ophthalmology (OPHTARA), 94270 Le Kremlin-Bicêtre, FranceOcular manifestations are a feature of West Nile virus infection. They mostly occur in association with severe neuroinvasive disease. Linear chorioretinitis is suggestive of the diagnosis and may raise diagnostic suspicion when associated with evocative systemic signs, and in an epidemic context. Various other less specific inflammatory ocular manifestations have been reported, including anterior uveitis, occlusive retinal vasculitis, optic neuritis, and diplopia. The pathophysiology of ocular disease remains unclear, but it reflects the neuroinvasiveness of the disease. Although ocular involvement most often resolves without visual sequelae, some patients may have permanent loss of vision, adding to the need for the development of a specific treatment and/or vaccines.https://www.mdpi.com/2076-393X/8/4/641West Nile virusocular involvementchorioretinitisretinal vasculitisuveitis |
| spellingShingle | Antoine Rousseau Oscar Haigh Imen Ksiaa Moncef Khairallah Marc Labetoulle Ocular Manifestations of West Nile Virus Vaccines West Nile virus ocular involvement chorioretinitis retinal vasculitis uveitis |
| title | Ocular Manifestations of West Nile Virus |
| title_full | Ocular Manifestations of West Nile Virus |
| title_fullStr | Ocular Manifestations of West Nile Virus |
| title_full_unstemmed | Ocular Manifestations of West Nile Virus |
| title_short | Ocular Manifestations of West Nile Virus |
| title_sort | ocular manifestations of west nile virus |
| topic | West Nile virus ocular involvement chorioretinitis retinal vasculitis uveitis |
| url | https://www.mdpi.com/2076-393X/8/4/641 |
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