Cinnamon extract enhances glucose uptake in 3T3-L1 adipocytes and C2C12 myocytes by inducing LKB1-AMP-activated protein kinase signaling.

We previously demonstrated that cinnamon extract (CE) ameliorates type 1 diabetes induced by streptozotocin in rats through the up-regulation of glucose transporter 4 (GLUT4) translocation in both muscle and adipose tissues. This present study was aimed at clarifying the detailed mechanism(s) with w...

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Bibliographic Details
Main Authors: Yan Shen, Natsumi Honma, Katsuya Kobayashi, Liu Nan Jia, Takashi Hosono, Kazutoshi Shindo, Toyohiko Ariga, Taiichiro Seki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3925101?pdf=render