Oxidative Stress as an Underlying Mechanism of Bacteria-Inflicted Damage to Male Gametes
Bacterial infestation of the male reproductive system with subsequent effects of bacteria on the structural integrity and functional activity of male gametes has become a significant factor in the etiology of male reproductive dysfunction. Bacteria may affect male fertility either by directly intera...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-11-01
|
| Series: | Oxygen |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2673-9801/2/4/36 |
| _version_ | 1797455840119095296 |
|---|---|
| author | Eva Tvrdá Filip Benko Michal Ďuračka |
| author_facet | Eva Tvrdá Filip Benko Michal Ďuračka |
| author_sort | Eva Tvrdá |
| collection | DOAJ |
| description | Bacterial infestation of the male reproductive system with subsequent effects of bacteria on the structural integrity and functional activity of male gametes has become a significant factor in the etiology of male reproductive dysfunction. Bacteria may affect male fertility either by directly interacting with structures critical for sperm survival or indirectly by triggering a local immune response, leukocytospermia or reactive oxygen species (ROS) overproduction followed by oxidative stress development. This review aims to provide an overview of the currently available knowledge on bacteriospermia-associated sperm damage with a special emphasis on oxidative mechanisms underlying sperm deterioration caused by bacterial action. At the same time, we strive to summarize readily available alternatives to prevent or counteract alterations to spermatozoa caused by bacterial colonization of semen or by oxidative stress as an accompanying phenomenon of bacteriospermia. |
| first_indexed | 2024-03-09T15:59:59Z |
| format | Article |
| id | doaj.art-16445bda9b25438fbe459f03fe650038 |
| institution | Directory Open Access Journal |
| issn | 2673-9801 |
| language | English |
| last_indexed | 2024-03-09T15:59:59Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Oxygen |
| spelling | doaj.art-16445bda9b25438fbe459f03fe6500382023-11-24T17:11:37ZengMDPI AGOxygen2673-98012022-11-012454756910.3390/oxygen2040036Oxidative Stress as an Underlying Mechanism of Bacteria-Inflicted Damage to Male GametesEva Tvrdá0Filip Benko1Michal Ďuračka2Institute of Biotechnology, Faculty of Biotechnology and Food Sciences, Slovak University of Agriculture in Nitra, Tr. A. Hlinku 2, 94976 Nitra, SlovakiaInstitute of Applied Biology, Faculty of Biotechnology and Food Sciences, Slovak University of Agriculture in Nitra, Tr. A. Hlinku 2, 94976 Nitra, SlovakiaAgroBioTech Research Centre, Slovak University of Agriculture in Nitra, Tr. A. Hlinku 2, 94976 Nitra, SlovakiaBacterial infestation of the male reproductive system with subsequent effects of bacteria on the structural integrity and functional activity of male gametes has become a significant factor in the etiology of male reproductive dysfunction. Bacteria may affect male fertility either by directly interacting with structures critical for sperm survival or indirectly by triggering a local immune response, leukocytospermia or reactive oxygen species (ROS) overproduction followed by oxidative stress development. This review aims to provide an overview of the currently available knowledge on bacteriospermia-associated sperm damage with a special emphasis on oxidative mechanisms underlying sperm deterioration caused by bacterial action. At the same time, we strive to summarize readily available alternatives to prevent or counteract alterations to spermatozoa caused by bacterial colonization of semen or by oxidative stress as an accompanying phenomenon of bacteriospermia.https://www.mdpi.com/2673-9801/2/4/36bacteriospermiainfectionsperm qualityoxidative stressreactive oxygen speciessubfertility |
| spellingShingle | Eva Tvrdá Filip Benko Michal Ďuračka Oxidative Stress as an Underlying Mechanism of Bacteria-Inflicted Damage to Male Gametes Oxygen bacteriospermia infection sperm quality oxidative stress reactive oxygen species subfertility |
| title | Oxidative Stress as an Underlying Mechanism of Bacteria-Inflicted Damage to Male Gametes |
| title_full | Oxidative Stress as an Underlying Mechanism of Bacteria-Inflicted Damage to Male Gametes |
| title_fullStr | Oxidative Stress as an Underlying Mechanism of Bacteria-Inflicted Damage to Male Gametes |
| title_full_unstemmed | Oxidative Stress as an Underlying Mechanism of Bacteria-Inflicted Damage to Male Gametes |
| title_short | Oxidative Stress as an Underlying Mechanism of Bacteria-Inflicted Damage to Male Gametes |
| title_sort | oxidative stress as an underlying mechanism of bacteria inflicted damage to male gametes |
| topic | bacteriospermia infection sperm quality oxidative stress reactive oxygen species subfertility |
| url | https://www.mdpi.com/2673-9801/2/4/36 |
| work_keys_str_mv | AT evatvrda oxidativestressasanunderlyingmechanismofbacteriainflicteddamagetomalegametes AT filipbenko oxidativestressasanunderlyingmechanismofbacteriainflicteddamagetomalegametes AT michalduracka oxidativestressasanunderlyingmechanismofbacteriainflicteddamagetomalegametes |