Gastrointestinal Ischemia—Stumbling Stone in COVID-19 Patients
The emergence of the novel SARS-CoV2 virus, proclaimed by the World Health Organization (WHO) as a culpable agent for the pandemic situation, caught the scientific and medical communities off guard. One of the most common complications following pulmonary disease is represented by gastrointestinal (...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-06-01
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| Series: | Gastroenterology Insights |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2036-7422/13/2/21 |
| _version_ | 1797487217309908992 |
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| author | Monika Peshevska-Sekulovska Irina Boeva Metodija Sekulovski Miroslav Zashev Milena Peruhova |
| author_facet | Monika Peshevska-Sekulovska Irina Boeva Metodija Sekulovski Miroslav Zashev Milena Peruhova |
| author_sort | Monika Peshevska-Sekulovska |
| collection | DOAJ |
| description | The emergence of the novel SARS-CoV2 virus, proclaimed by the World Health Organization (WHO) as a culpable agent for the pandemic situation, caught the scientific and medical communities off guard. One of the most common complications following pulmonary disease is represented by gastrointestinal (GI) disorders, especially ischemic damage. Inflammation, vasculopathy, immobility, endothelial dysfunction, and a hypercoagulable condition have all been proposed as pathophysiological factors for GI ischemia in these patients. Owing to the COVID-19 effect on a variety of GI conditions, especially ischemic changes, and the high mortality rate, physicians should always keep in mind this complication. They should take a deeper look at clinical and imaging modalities in this cohort of patients so that a proper and time-saving treatment strategy can be applied. Our study aimed to elucidate the thrombogenic mechanism in different GI disorders. Moreover, we analyzed the factors related to necrotic GI changes, by summarizing the already reported data of GI ischemia in COVID-19. To the best of our knowledge, this review is the first to incorporate all GI ischemia cases reported in the literature so far. |
| first_indexed | 2024-03-09T23:44:30Z |
| format | Article |
| id | doaj.art-16452a85a411419fb49c2a3f1cf8d72e |
| institution | Directory Open Access Journal |
| issn | 2036-7414 2036-7422 |
| language | English |
| last_indexed | 2024-03-09T23:44:30Z |
| publishDate | 2022-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Gastroenterology Insights |
| spelling | doaj.art-16452a85a411419fb49c2a3f1cf8d72e2023-11-23T16:44:51ZengMDPI AGGastroenterology Insights2036-74142036-74222022-06-0113220621710.3390/gastroent13020021Gastrointestinal Ischemia—Stumbling Stone in COVID-19 PatientsMonika Peshevska-Sekulovska0Irina Boeva1Metodija Sekulovski2Miroslav Zashev3Milena Peruhova4University Hospital “Lozenetz”, 1407 Sofia, BulgariaUniversity Hospital “Heart and Brain”, 1172 Burgas, BulgariaUniversity Hospital “Lozenetz”, 1407 Sofia, BulgariaUniversity Hospital “Heart and Brain”, 1172 Burgas, BulgariaUniversity Hospital “Heart and Brain”, 1172 Burgas, BulgariaThe emergence of the novel SARS-CoV2 virus, proclaimed by the World Health Organization (WHO) as a culpable agent for the pandemic situation, caught the scientific and medical communities off guard. One of the most common complications following pulmonary disease is represented by gastrointestinal (GI) disorders, especially ischemic damage. Inflammation, vasculopathy, immobility, endothelial dysfunction, and a hypercoagulable condition have all been proposed as pathophysiological factors for GI ischemia in these patients. Owing to the COVID-19 effect on a variety of GI conditions, especially ischemic changes, and the high mortality rate, physicians should always keep in mind this complication. They should take a deeper look at clinical and imaging modalities in this cohort of patients so that a proper and time-saving treatment strategy can be applied. Our study aimed to elucidate the thrombogenic mechanism in different GI disorders. Moreover, we analyzed the factors related to necrotic GI changes, by summarizing the already reported data of GI ischemia in COVID-19. To the best of our knowledge, this review is the first to incorporate all GI ischemia cases reported in the literature so far.https://www.mdpi.com/2036-7422/13/2/21COVID-19gastrointestinal ischemiaischemic colitisnecrotic esophagitismesenteric thrombosis |
| spellingShingle | Monika Peshevska-Sekulovska Irina Boeva Metodija Sekulovski Miroslav Zashev Milena Peruhova Gastrointestinal Ischemia—Stumbling Stone in COVID-19 Patients Gastroenterology Insights COVID-19 gastrointestinal ischemia ischemic colitis necrotic esophagitis mesenteric thrombosis |
| title | Gastrointestinal Ischemia—Stumbling Stone in COVID-19 Patients |
| title_full | Gastrointestinal Ischemia—Stumbling Stone in COVID-19 Patients |
| title_fullStr | Gastrointestinal Ischemia—Stumbling Stone in COVID-19 Patients |
| title_full_unstemmed | Gastrointestinal Ischemia—Stumbling Stone in COVID-19 Patients |
| title_short | Gastrointestinal Ischemia—Stumbling Stone in COVID-19 Patients |
| title_sort | gastrointestinal ischemia stumbling stone in covid 19 patients |
| topic | COVID-19 gastrointestinal ischemia ischemic colitis necrotic esophagitis mesenteric thrombosis |
| url | https://www.mdpi.com/2036-7422/13/2/21 |
| work_keys_str_mv | AT monikapeshevskasekulovska gastrointestinalischemiastumblingstoneincovid19patients AT irinaboeva gastrointestinalischemiastumblingstoneincovid19patients AT metodijasekulovski gastrointestinalischemiastumblingstoneincovid19patients AT miroslavzashev gastrointestinalischemiastumblingstoneincovid19patients AT milenaperuhova gastrointestinalischemiastumblingstoneincovid19patients |