Multicomponent Analysis of the Differential Induction of Secondary Metabolite Profiles in Fungal Endophytes

Multicomponent Analysis of the Differential Induction of Secondary Metabolite Profiles in Fungal Endophytes

Small molecule histone deacetylase (HDAC) and DNA methyltransferase (DNMT) inhibitors are commonly used to perturb the production of fungal metabolites leading to the induction of the expression of silent biosynthetic pathways. Several reports have described the variable effects observed in natural...

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Bibliographic Details
Main Authors: Víctor González-Menéndez, Mercedes Pérez-Bonilla, Ignacio Pérez-Victoria, Jesús Martín, Francisca Muñoz, Fernando Reyes, José R. Tormo, Olga Genilloud
Format: Article
Language:English
Published: MDPI AG 2016-02-01
Series:Molecules
Subjects:
fungal endophytes
epigenetic modifiers
HDAC
DNMT
volcano plots
secondary metabolites
metabolomics
Online Access:http://www.mdpi.com/1420-3049/21/2/234

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