Synchronous mucinous metaplasia and neoplasia of the female genital tract with both pulmonary metastases and STK11/KRAS gene mutations: a case report

Synchronous mucinous metaplasia and neoplasia of the female genital tract with both pulmonary metastases and STK11/KRAS gene mutations: a case report

Multiple morphological changes in two or more sites of concurrent multifocal mucinous lesions in the female genital tract are indicative of SMMN-FGT, which is unrelated to high-risk HPV infection. MUC6 and HIK-1083 showed positive characteristic immunohistochemistry. Seldom is the condition describe...

Full description

Bibliographic Details
Main Authors:	Ru Wang, Hao Yu, Ming Liu, Ting Hao, Xiangyu Wang, Lianbao Cao
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-11-01
Series:	Frontiers in Oncology
Subjects:	SMMN-FGT STK11 KRAS pulmonary metastases gene mutations
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2023.1246821/full

Similar Items

The prognostic impact of KRAS, TP53, STK11 and KEAP1 mutations and their influence on the NLR in NSCLC patients treated with immunotherapy
by: Francis Proulx-Rocray, et al.
Published: (2023-01-01)

Targeting KRAS in Lung Cancer Beyond KRAS G12C Inhibitors: The Immune Regulatory Role of KRAS and Novel Therapeutic Strategies
by: Marc Cucurull, et al.
Published: (2022-01-01)

TP53 co-mutations in advanced lung adenocarcinoma: comparative bioinformatic analyses suggest ambivalent character on overall survival alongside KRAS, STK11 and KEAP1 mutations
by: Armin Frille, et al.
Published: (2024-04-01)

Corrigendum: TP53 co-mutations in advanced lung adenocarcinoma: comparative bioinformatic analyses suggest ambivalent character on overall survival alongside KRAS, STK11 and KEAP1 mutations
by: Armin Frille, et al.
Published: (2024-09-01)

When synchronous mucinous metaplasia and neoplasia of the female genital tract and peutz-jeghers syndrome meet: a case report and literature reviews
by: Yue Zhou, et al.
Published: (2024-06-01)

KRAS genotypes predict metachronous colorectal cancer distant metastases after radical resections
by: LIN Songbin, FENG Qingyang, XU Jianmin
Published: (2021-01-01)

Sotorasib Shows Intracranial Activity in Patients with KRAS G12C-Mutated Adenocarcinoma of the Lung and Untreated Active Brain Metastases
by: Kira-Lee Koster, et al.
Published: (2022-08-01)

Incidence Of Kras Mutations In Colon Adenocarcinomas And Its Association With Lymph Node Metastases
by: Gökhan Varlı, et al.
Published: (2020-06-01)

Overall survival in patients with advanced non-small cell lung cancer with KRAS G12C mutation with or without STK11 and/or KEAP1 mutations in a real-world setting
by: Cristina Julian, et al.
Published: (2023-04-01)

NPRL2 gene therapy induces effective antitumor immunity in KRAS/STK11 mutant anti-PD1 resistant metastatic non-small cell lung cancer (NSCLC) in a humanized mouse model
by: Ismail M Meraz, et al.
Published: (2025-02-01)

Differential effects of KRAS mutational status on long-term survival according to the timing of colorectal liver metastases
by: Nozomu Sakai, et al.
Published: (2021-04-01)

<i>STK11/LKB1</i> Modulation of the Immune Response in Lung Cancer: From Biology to Therapeutic Impact
by: Elvire Pons-Tostivint, et al.
Published: (2021-11-01)

Mechanistic Insights into the Mechanism of Inhibitor Selectivity toward the Dark Kinase STK17B against Its High Homology STK17A
by: Chang Liu, et al.
Published: (2022-07-01)

OTİZM MİSYONLARINA SAHİP STK’LARDA GÖNÜLLÜ FAALİYETLERİNE ETKİ EDEN FAKTÖRLER: İZMİR İLİ ÖRNEĞİ
by: Nezih Metin Özmutaf, et al.
Published: (2017-06-01)

STK3-ALK, a Novel ALK Rearrangement in Non-Small Cell Lung Cancer With Sensitivity to Tyrosine Kinase Inhibitors: A Case Report
by: Chunlai Feng, et al.
Published: (2021-08-01)

Activity of sotorasib against brain metastases from NSCLC harboring KRAS p.G12C mutation: a case report
by: Alessandro Inno, et al.
Published: (2023-06-01)

Identification and characterization of alternative STK39 transcripts within human and mouse kidneys reveals species‐specific regulation of blood pressure
by: Carlo J. Mercado, et al.
Published: (2020-02-01)

STK16 promoted colorectal cancer progress in a c-MYC signaling-dependent manner
by: Li Peng, et al.
Published: (2024-04-01)

Stk10 Deficiency in Mice Promotes Tumor Growth by Dysregulating the Tumor Microenvironment
by: Jin-Xia Ma, et al.
Published: (2022-11-01)

An Effective Procedure to Build Space Object Datasets Based on STK
by: Rongke Wei, et al.
Published: (2023-03-01)

Cancer‐testis gene STK31 is regulated by methylation and promotes the development of pancreatic cancer
by: Hao Gao, et al.
Published: (2023-03-01)

STK11 genetic alterations in metastatic EGFR mutant lung cancer
by: Dandan Yin, et al.
Published: (2025-02-01)

Receptor-Like Cytoplasmic Kinase STK Confers Salt Tolerance in Rice
by: Yanbiao Zhou, et al.
Published: (2023-04-01)

The Importance of <i>STK11</i>/<i>LKB1</i> Assessment in Non-Small Cell Lung Carcinomas
by: Baharia Mograbi, et al.
Published: (2021-01-01)

Body representation in infants: Categorical boundaries of body parts as assessed by somatosensory mismatch negativity
by: Guannan Shen, et al.
Published: (2020-08-01)

Downregulation of STK4 promotes colon cancer invasion/migration through blocking β‐catenin degradation
by: Cheng‐Han Lin, et al.
Published: (2020-10-01)

The value of KRAS gene status in predicting local tumor progression of colorectal liver metastases following radiofrequency ablation
by: Bin-bin Jiang, et al.
Published: (2019-01-01)

Somatic mutations of <it>STK11</it> gene in human papillomavirus positive and negative penile cancer
by: Annunziata Clorinda, et al.
Published: (2013-01-01)

Correlation Between STK11 Gene Mutation and Immunotherapy of Non-small Cell Lung Cancer
by: XIA Siyu, et al.
Published: (2022-08-01)

Towards precision medicine in colorectal cancer liver metastases
by: Juan Manuel O’Connor, et al.
Published: (2020-09-01)

Comparison of EGFR and KRAS Status between Primary Non-small Cell Lung Cancer and Corresponding Metastases: A Systematic Review and meta-analysis
by: Chengbo HAN, et al.
Published: (2010-09-01)

ÇEVRE EĞİTİMİNDE KAMUSAL HALKLA İLİŞKİLER VE STK'LAR İLE İŞBİRLİĞİ
by: Elif Şeşen
Published: (2015-08-01)

Correlation between KRAS and NRAS mutational status and clinicopathological features in 414 cases of metastatic colorectal cancer in Morocco: the largest North African case series
by: Youssef Mahdi, et al.
Published: (2023-06-01)

STK25 enhances hepatocellular carcinoma progression through the STRN/AMPK/ACC1 pathway
by: Yichao Zhang, et al.
Published: (2022-01-01)

The role of LKB1 (STK11) in non-small cell lung cancer
by: Cahill, F
Published: (2017)

A novel missense mutation of the STK11 gene in a Chinese family with Peutz-Jeghers syndrome
by: Zhen Yu, et al.
Published: (2022-12-01)

Systematic analysis of prognostic significance, functional enrichment and immune implication of STK10 in acute myeloid leukemia
by: Lei Bi, et al.
Published: (2022-05-01)

Deletion of Stk11 and Fos in mouse BLA projection neurons alters intrinsic excitability and impairs formation of long-term aversive memory
by: David Levitan, et al.
Published: (2020-08-01)

Evaluation of KRAS inhibitor-directed therapies for pancreatic cancer treatment
by: Szu-Aun Long, et al.
Published: (2024-05-01)

Transcriptomic Changes Resulting From STK32B Overexpression Identify Pathways Potentially Relevant to Essential Tremor
by: Calwing Liao, et al.
Published: (2020-07-01)