Implementing a pharmacist-integrated collaborative model of medication treatment for opioid use disorder in primary care: study design and methodological considerations
Abstract Background Pharmacists remain an underutilized resource in the treatment of opioid use disorder (OUD). Although studies have engaged pharmacists in dispensing medications for OUD (MOUD), few studies have evaluated collaborative care models in which pharmacists are an active, integrated part...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2024-03-01
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| Series: | Addiction Science & Clinical Practice |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13722-024-00452-y |
| _version_ | 1797247112927248384 |
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| author | Bethany McLeman Phoebe Gauthier Laurie S. Lester Felicity Homsted Vernon Gardner Sarah K. Moore Paul J. Joudrey Lisa Saldana Gerald Cochran Jacklyn P. Harris Kathryn Hefner Edward Chongsi Kimberly Kramer Ashley Vena Rebecca A. Ottesen Tess Gallant Jesse S. Boggis Deepika Rao Marjorie Page Nicholas Cox Michelle Iandiorio Ekow Ambaah Udi Ghitza David A. Fiellin Lisa A. Marsch |
| author_facet | Bethany McLeman Phoebe Gauthier Laurie S. Lester Felicity Homsted Vernon Gardner Sarah K. Moore Paul J. Joudrey Lisa Saldana Gerald Cochran Jacklyn P. Harris Kathryn Hefner Edward Chongsi Kimberly Kramer Ashley Vena Rebecca A. Ottesen Tess Gallant Jesse S. Boggis Deepika Rao Marjorie Page Nicholas Cox Michelle Iandiorio Ekow Ambaah Udi Ghitza David A. Fiellin Lisa A. Marsch |
| author_sort | Bethany McLeman |
| collection | DOAJ |
| description | Abstract Background Pharmacists remain an underutilized resource in the treatment of opioid use disorder (OUD). Although studies have engaged pharmacists in dispensing medications for OUD (MOUD), few studies have evaluated collaborative care models in which pharmacists are an active, integrated part of a primary care team offering OUD care. Methods This study seeks to implement a pharmacist integrated MOUD clinical model (called PrIMO) and evaluate its feasibility, acceptability, and impact across four diverse primary care sites. The Consolidated Framework for Implementation Research is used as an organizing framework for study development and interpretation of findings. Implementation Facilitation is used to support PrIMO adoption. We assess the primary outcome, the feasibility of implementing PrIMO, using the Stages of Implementation Completion (SIC). We evaluate the acceptability and impact of the PrIMO model at the sites using mixed-methods and combine survey and interview data from providers, pharmacists, pharmacy technicians, administrators, and patients receiving MOUD at the primary care sites with patient electronic health record data. We hypothesize that it is feasible to launch delivery of the PrIMO model (reach SIC Stage 6), and that it is acceptable, will positively impact patient outcomes 1 year post model launch (e.g., increased MOUD treatment retention, medication regimen adherence, service utilization for co-morbid conditions, and decreased substance use), and will increase each site’s capacity to care for patients with MOUD (e.g., increased number of patients, number of prescribers, and rate of patients per prescriber). Discussion This study will provide data on a pharmacist-integrated collaborative model of care for the treatment of OUD that may be feasible, acceptable to both site staff and patients and may favorably impact patients’ access to MOUD and treatment outcomes. Trial registration: The study was registered on Clinicaltrials.gov (NCT05310786) on April 5, 2022, https://www.clinicaltrials.gov/study/NCT05310786?id=NCT05310786&rank=1 |
| first_indexed | 2024-04-24T19:53:31Z |
| format | Article |
| id | doaj.art-164c9bf7b10a421f9593acdd1b5a4426 |
| institution | Directory Open Access Journal |
| issn | 1940-0640 |
| language | English |
| last_indexed | 2024-04-24T19:53:31Z |
| publishDate | 2024-03-01 |
| publisher | BMC |
| record_format | Article |
| series | Addiction Science & Clinical Practice |
| spelling | doaj.art-164c9bf7b10a421f9593acdd1b5a44262024-03-24T12:28:41ZengBMCAddiction Science & Clinical Practice1940-06402024-03-0119111310.1186/s13722-024-00452-yImplementing a pharmacist-integrated collaborative model of medication treatment for opioid use disorder in primary care: study design and methodological considerationsBethany McLeman0Phoebe Gauthier1Laurie S. Lester2Felicity Homsted3Vernon Gardner4Sarah K. Moore5Paul J. Joudrey6Lisa Saldana7Gerald Cochran8Jacklyn P. Harris9Kathryn Hefner10Edward Chongsi11Kimberly Kramer12Ashley Vena13Rebecca A. Ottesen14Tess Gallant15Jesse S. Boggis16Deepika Rao17Marjorie Page18Nicholas Cox19Michelle Iandiorio20Ekow Ambaah21Udi Ghitza22David A. Fiellin23Lisa A. Marsch24Northeast Node, NIDA Drug Abuse Treatment Clinical Trials NetworkNortheast Node, NIDA Drug Abuse Treatment Clinical Trials NetworkNortheast Node, NIDA Drug Abuse Treatment Clinical Trials NetworkFQHC 340B ComplianceNortheast Node, NIDA Drug Abuse Treatment Clinical Trials NetworkNortheast Node, NIDA Drug Abuse Treatment Clinical Trials NetworkUniversity of Pittsburgh School of MedicineLighthouse Institute, Chestnut Health SystemsUniversity of UtahThe Emmes Company, LLCThe Emmes Company, LLCThe Emmes Company, LLCThe Emmes Company, LLCThe Emmes Company, LLCThe Emmes Company, LLCNortheast Node, NIDA Drug Abuse Treatment Clinical Trials NetworkCenter for Technology and Behavioral Health, Geisel School of Medicine at Dartmouth CollegeCenter for Technology and Behavioral Health, Geisel School of Medicine at Dartmouth CollegeCommunity Health CareUniversity of Utah College of PharmacyUniversity of New Mexico School of MedicineHarbor Care Health & WellnessNational Institute on Drug AbuseNew England Consortium Node, NIDA Drug Abuse Treatment Clinical Trials NetworkNortheast Node, NIDA Drug Abuse Treatment Clinical Trials NetworkAbstract Background Pharmacists remain an underutilized resource in the treatment of opioid use disorder (OUD). Although studies have engaged pharmacists in dispensing medications for OUD (MOUD), few studies have evaluated collaborative care models in which pharmacists are an active, integrated part of a primary care team offering OUD care. Methods This study seeks to implement a pharmacist integrated MOUD clinical model (called PrIMO) and evaluate its feasibility, acceptability, and impact across four diverse primary care sites. The Consolidated Framework for Implementation Research is used as an organizing framework for study development and interpretation of findings. Implementation Facilitation is used to support PrIMO adoption. We assess the primary outcome, the feasibility of implementing PrIMO, using the Stages of Implementation Completion (SIC). We evaluate the acceptability and impact of the PrIMO model at the sites using mixed-methods and combine survey and interview data from providers, pharmacists, pharmacy technicians, administrators, and patients receiving MOUD at the primary care sites with patient electronic health record data. We hypothesize that it is feasible to launch delivery of the PrIMO model (reach SIC Stage 6), and that it is acceptable, will positively impact patient outcomes 1 year post model launch (e.g., increased MOUD treatment retention, medication regimen adherence, service utilization for co-morbid conditions, and decreased substance use), and will increase each site’s capacity to care for patients with MOUD (e.g., increased number of patients, number of prescribers, and rate of patients per prescriber). Discussion This study will provide data on a pharmacist-integrated collaborative model of care for the treatment of OUD that may be feasible, acceptable to both site staff and patients and may favorably impact patients’ access to MOUD and treatment outcomes. Trial registration: The study was registered on Clinicaltrials.gov (NCT05310786) on April 5, 2022, https://www.clinicaltrials.gov/study/NCT05310786?id=NCT05310786&rank=1https://doi.org/10.1186/s13722-024-00452-yPharmacistsEvidence-based pharmacy practiceOpioid use disorderImplementation scienceFeasibility studiesMedications for opioid use disorder |
| spellingShingle | Bethany McLeman Phoebe Gauthier Laurie S. Lester Felicity Homsted Vernon Gardner Sarah K. Moore Paul J. Joudrey Lisa Saldana Gerald Cochran Jacklyn P. Harris Kathryn Hefner Edward Chongsi Kimberly Kramer Ashley Vena Rebecca A. Ottesen Tess Gallant Jesse S. Boggis Deepika Rao Marjorie Page Nicholas Cox Michelle Iandiorio Ekow Ambaah Udi Ghitza David A. Fiellin Lisa A. Marsch Implementing a pharmacist-integrated collaborative model of medication treatment for opioid use disorder in primary care: study design and methodological considerations Addiction Science & Clinical Practice Pharmacists Evidence-based pharmacy practice Opioid use disorder Implementation science Feasibility studies Medications for opioid use disorder |
| title | Implementing a pharmacist-integrated collaborative model of medication treatment for opioid use disorder in primary care: study design and methodological considerations |
| title_full | Implementing a pharmacist-integrated collaborative model of medication treatment for opioid use disorder in primary care: study design and methodological considerations |
| title_fullStr | Implementing a pharmacist-integrated collaborative model of medication treatment for opioid use disorder in primary care: study design and methodological considerations |
| title_full_unstemmed | Implementing a pharmacist-integrated collaborative model of medication treatment for opioid use disorder in primary care: study design and methodological considerations |
| title_short | Implementing a pharmacist-integrated collaborative model of medication treatment for opioid use disorder in primary care: study design and methodological considerations |
| title_sort | implementing a pharmacist integrated collaborative model of medication treatment for opioid use disorder in primary care study design and methodological considerations |
| topic | Pharmacists Evidence-based pharmacy practice Opioid use disorder Implementation science Feasibility studies Medications for opioid use disorder |
| url | https://doi.org/10.1186/s13722-024-00452-y |
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