Core biopsies of the breast: Diagnostic pitfalls
The incidence of breast cancer is increasing worldwide. In this review article, the authors compare and contrast the incidence of breast cancer, and the inherent differences in the United States (US) and India in screening techniques used for diagnosing breast cancer. In spite of these differences,...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2011-01-01
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| Series: | Indian Journal of Pathology and Microbiology |
| Subjects: | |
| Online Access: | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2011;volume=54;issue=4;spage=671;epage=682;aulast=Joshi |
| _version_ | 1811343397359714304 |
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| author | Megha Joshi Sriharshan J Reddy Manjiri Nanavidekar John P Russo Armand V Russo Ram Pathak |
| author_facet | Megha Joshi Sriharshan J Reddy Manjiri Nanavidekar John P Russo Armand V Russo Ram Pathak |
| author_sort | Megha Joshi |
| collection | DOAJ |
| description | The incidence of breast cancer is increasing worldwide. In this review article, the authors compare and contrast the incidence of breast cancer, and the inherent differences in the United States (US) and India in screening techniques used for diagnosing breast cancer. In spite of these differences, core biopsies of the breast are common for diagnosis of breast cancer in both countries. The authors describe "Best Practices" in the reporting and processing of core biopsies and in the analysis of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor Receptor 2 (Her2/neu). The pitfalls in the diagnosis of fibroepithelial lesions of the breast on core biopsy are discussed, as also the significance of pseudoangiomatous stromal hyperplasia of the breast (PASH) is discussed in core biopsy. In this review, the management and diagnosis of flat epithelial atypia and radiation atypia are elaborated and the use of immunohistochemistry (IHC) in papillary lesions, phyllodes tumor, and complex sclerosing lesions (radial scars) is illustrated. Rarer lesions such as mucinous and histiocytoid carcinoma are also discussed. |
| first_indexed | 2024-04-13T19:28:41Z |
| format | Article |
| id | doaj.art-164d6c9bc7ab41058a28ff7d35dd51c3 |
| institution | Directory Open Access Journal |
| issn | 0377-4929 |
| language | English |
| last_indexed | 2024-04-13T19:28:41Z |
| publishDate | 2011-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Pathology and Microbiology |
| spelling | doaj.art-164d6c9bc7ab41058a28ff7d35dd51c32022-12-22T02:33:14ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49292011-01-0154467168210.4103/0377-4929.91490Core biopsies of the breast: Diagnostic pitfallsMegha JoshiSriharshan J ReddyManjiri NanavidekarJohn P RussoArmand V RussoRam PathakThe incidence of breast cancer is increasing worldwide. In this review article, the authors compare and contrast the incidence of breast cancer, and the inherent differences in the United States (US) and India in screening techniques used for diagnosing breast cancer. In spite of these differences, core biopsies of the breast are common for diagnosis of breast cancer in both countries. The authors describe "Best Practices" in the reporting and processing of core biopsies and in the analysis of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor Receptor 2 (Her2/neu). The pitfalls in the diagnosis of fibroepithelial lesions of the breast on core biopsy are discussed, as also the significance of pseudoangiomatous stromal hyperplasia of the breast (PASH) is discussed in core biopsy. In this review, the management and diagnosis of flat epithelial atypia and radiation atypia are elaborated and the use of immunohistochemistry (IHC) in papillary lesions, phyllodes tumor, and complex sclerosing lesions (radial scars) is illustrated. Rarer lesions such as mucinous and histiocytoid carcinoma are also discussed.http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2011;volume=54;issue=4;spage=671;epage=682;aulast=JoshiBreastbiopsybreast cancercarcinomaductal carcinoma in situERfibroepithelial lesionsHer2-neuPRphyllodes tumor |
| spellingShingle | Megha Joshi Sriharshan J Reddy Manjiri Nanavidekar John P Russo Armand V Russo Ram Pathak Core biopsies of the breast: Diagnostic pitfalls Indian Journal of Pathology and Microbiology Breast biopsy breast cancer carcinoma ductal carcinoma in situ ER fibroepithelial lesions Her2-neu PR phyllodes tumor |
| title | Core biopsies of the breast: Diagnostic pitfalls |
| title_full | Core biopsies of the breast: Diagnostic pitfalls |
| title_fullStr | Core biopsies of the breast: Diagnostic pitfalls |
| title_full_unstemmed | Core biopsies of the breast: Diagnostic pitfalls |
| title_short | Core biopsies of the breast: Diagnostic pitfalls |
| title_sort | core biopsies of the breast diagnostic pitfalls |
| topic | Breast biopsy breast cancer carcinoma ductal carcinoma in situ ER fibroepithelial lesions Her2-neu PR phyllodes tumor |
| url | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2011;volume=54;issue=4;spage=671;epage=682;aulast=Joshi |
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