Ischemic Heart Disease during Acute Exacerbations of COPD
Patients with chronic obstructive pulmonary disease (COPD) have a higher risk of acute cardiovascular events, and around 30% die from cardiovascular diseases. Recent data suggest an increased risk of myocardial infarction in the following days of a severe exacerbation of COPD. Disruption in the bala...
| Main Authors: | , , , , |
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| Format: | Article |
| Sprog: | English |
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MDPI AG
2018-09-01
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| Serier: | Medical Sciences |
| Fag: | |
| Online adgang: | http://www.mdpi.com/2076-3271/6/4/83 |
| _version_ | 1828203354390528000 |
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| author | Rosa Malo de Molina Silvia Aguado Carlos Arellano Manuel Valle Piedad Ussetti |
| author_facet | Rosa Malo de Molina Silvia Aguado Carlos Arellano Manuel Valle Piedad Ussetti |
| author_sort | Rosa Malo de Molina |
| collection | DOAJ |
| description | Patients with chronic obstructive pulmonary disease (COPD) have a higher risk of acute cardiovascular events, and around 30% die from cardiovascular diseases. Recent data suggest an increased risk of myocardial infarction in the following days of a severe exacerbation of COPD. Disruption in the balance during the exacerbation with tachycardia, increased inflammation and systemic oxidative stress as well as some other factors may confer an increased risk of subsequent cardiovascular events. A number of investigations may be useful to an early diagnosis, including electrocardiography, imaging techniques and blood test for biomarkers. Some drugs that have changed prognosis in the cardiovascular setting such as cardioselective beta-blockers may be underused in patients with COPD despite its demonstrated benefits. This review focuses on several aspects of exacerbation of COPD and cardiovascular events including epidemiology, possible mechanism, diagnosis and treatment. |
| first_indexed | 2024-04-12T12:03:11Z |
| format | Article |
| id | doaj.art-164f53a0046b4b3aa0b2f8b6e2bcdbb4 |
| institution | Directory Open Access Journal |
| issn | 2076-3271 |
| language | English |
| last_indexed | 2024-04-12T12:03:11Z |
| publishDate | 2018-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medical Sciences |
| spelling | doaj.art-164f53a0046b4b3aa0b2f8b6e2bcdbb42022-12-22T03:33:46ZengMDPI AGMedical Sciences2076-32712018-09-01648310.3390/medsci6040083medsci6040083Ischemic Heart Disease during Acute Exacerbations of COPDRosa Malo de Molina0Silvia Aguado1Carlos Arellano2Manuel Valle3Piedad Ussetti4Department of Pulmonary Medicine, University Hospital Puerta de Hierro, Majadahonda, 28040 Madrid, SpainDepartment of Pulmonary Medicine, University Hospital Puerta de Hierro, Majadahonda, 28040 Madrid, SpainDepartment of Cardiology, University Hospital Puerta de Hierro, Majadahonda, 28040 Madrid, SpainDepartment of Pulmonary Medicine, University Hospital Puerta de Hierro, Majadahonda, 28040 Madrid, SpainDepartment of Pulmonary Medicine, University Hospital Puerta de Hierro, Majadahonda, 28040 Madrid, SpainPatients with chronic obstructive pulmonary disease (COPD) have a higher risk of acute cardiovascular events, and around 30% die from cardiovascular diseases. Recent data suggest an increased risk of myocardial infarction in the following days of a severe exacerbation of COPD. Disruption in the balance during the exacerbation with tachycardia, increased inflammation and systemic oxidative stress as well as some other factors may confer an increased risk of subsequent cardiovascular events. A number of investigations may be useful to an early diagnosis, including electrocardiography, imaging techniques and blood test for biomarkers. Some drugs that have changed prognosis in the cardiovascular setting such as cardioselective beta-blockers may be underused in patients with COPD despite its demonstrated benefits. This review focuses on several aspects of exacerbation of COPD and cardiovascular events including epidemiology, possible mechanism, diagnosis and treatment.http://www.mdpi.com/2076-3271/6/4/83chronic obstructive pulmonary diseasecardiovascularmyocardial infarctionexacerbationtreatmentbeta-blockers |
| spellingShingle | Rosa Malo de Molina Silvia Aguado Carlos Arellano Manuel Valle Piedad Ussetti Ischemic Heart Disease during Acute Exacerbations of COPD Medical Sciences chronic obstructive pulmonary disease cardiovascular myocardial infarction exacerbation treatment beta-blockers |
| title | Ischemic Heart Disease during Acute Exacerbations of COPD |
| title_full | Ischemic Heart Disease during Acute Exacerbations of COPD |
| title_fullStr | Ischemic Heart Disease during Acute Exacerbations of COPD |
| title_full_unstemmed | Ischemic Heart Disease during Acute Exacerbations of COPD |
| title_short | Ischemic Heart Disease during Acute Exacerbations of COPD |
| title_sort | ischemic heart disease during acute exacerbations of copd |
| topic | chronic obstructive pulmonary disease cardiovascular myocardial infarction exacerbation treatment beta-blockers |
| url | http://www.mdpi.com/2076-3271/6/4/83 |
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