CCR5 as a Prognostic Factor in Lower-Grade Glioma is Involved in the Remodeling of the Tumor Microenvironment

CCR5 as a Prognostic Factor in Lower-Grade Glioma is Involved in the Remodeling of the Tumor Microenvironment

Background: Lower-grade gliomas (LGGs) carry a high risk of malignant transformation, leading to severe neurologic deterioration and ultimately, death. The tumor microenvironment (TME) plays an essential role in tumor maintenance, progression, and immunotherapy resistance. Therefore, the LGG TME des...

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Bibliographic Details
Main Authors: Fang Wang, Zhennan Tao, Zhen Tian, Jiaqi Jin, Jiawei Dong, Yuxiang Dai, Wanli Yu, Bin Tang, Shaoshan Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Genetics
Subjects:
tumor microenvironment
LGG
glioma
CCR5
immunological biomarker
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.874896/full

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