Optical Coherence Tomography Is a Promising Tool for Zebrafish-Based Research—A Review
The zebrafish is an established vertebrae model in the field of biomedical research. With its small size, rapid maturation time and semi-transparency at early development stages, it has proven to be an important animal model, especially for high-throughput studies. Three-dimensional, high-resolution...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-12-01
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| Series: | Bioengineering |
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| Online Access: | https://www.mdpi.com/2306-5354/10/1/5 |
| _version_ | 1797445992325316608 |
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| author | Antonia Lichtenegger Bernhard Baumann Yoshiaki Yasuno |
| author_facet | Antonia Lichtenegger Bernhard Baumann Yoshiaki Yasuno |
| author_sort | Antonia Lichtenegger |
| collection | DOAJ |
| description | The zebrafish is an established vertebrae model in the field of biomedical research. With its small size, rapid maturation time and semi-transparency at early development stages, it has proven to be an important animal model, especially for high-throughput studies. Three-dimensional, high-resolution, non-destructive and label-free imaging techniques are perfectly suited to investigate these animals over various development stages. Optical coherence tomography (OCT) is an interferometric-based optical imaging technique that has revolutionized the diagnostic possibilities in the field of ophthalmology and has proven to be a powerful tool for many microscopic applications. Recently, OCT found its way into state-of-the-art zebrafish-based research. This review article gives an overview and a discussion of the relevant literature and an outlook for this emerging field. |
| first_indexed | 2024-03-09T13:34:00Z |
| format | Article |
| id | doaj.art-16513df05e934066b3647a8792aab7a7 |
| institution | Directory Open Access Journal |
| issn | 2306-5354 |
| language | English |
| last_indexed | 2024-03-09T13:34:00Z |
| publishDate | 2022-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Bioengineering |
| spelling | doaj.art-16513df05e934066b3647a8792aab7a72023-11-30T21:14:07ZengMDPI AGBioengineering2306-53542022-12-01101510.3390/bioengineering10010005Optical Coherence Tomography Is a Promising Tool for Zebrafish-Based Research—A ReviewAntonia Lichtenegger0Bernhard Baumann1Yoshiaki Yasuno2Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, 1090 Vienna, AustriaCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, 1090 Vienna, AustriaComputational Optics Group, University of Tsukuba, Tsukuba 305-8573, JapanThe zebrafish is an established vertebrae model in the field of biomedical research. With its small size, rapid maturation time and semi-transparency at early development stages, it has proven to be an important animal model, especially for high-throughput studies. Three-dimensional, high-resolution, non-destructive and label-free imaging techniques are perfectly suited to investigate these animals over various development stages. Optical coherence tomography (OCT) is an interferometric-based optical imaging technique that has revolutionized the diagnostic possibilities in the field of ophthalmology and has proven to be a powerful tool for many microscopic applications. Recently, OCT found its way into state-of-the-art zebrafish-based research. This review article gives an overview and a discussion of the relevant literature and an outlook for this emerging field.https://www.mdpi.com/2306-5354/10/1/5zebrafishoptical coherence tomographyangiographypolarization-sensitivemulti-modal imaging pre-clinicalbiomedical research |
| spellingShingle | Antonia Lichtenegger Bernhard Baumann Yoshiaki Yasuno Optical Coherence Tomography Is a Promising Tool for Zebrafish-Based Research—A Review Bioengineering zebrafish optical coherence tomography angiography polarization-sensitive multi-modal imaging pre-clinical biomedical research |
| title | Optical Coherence Tomography Is a Promising Tool for Zebrafish-Based Research—A Review |
| title_full | Optical Coherence Tomography Is a Promising Tool for Zebrafish-Based Research—A Review |
| title_fullStr | Optical Coherence Tomography Is a Promising Tool for Zebrafish-Based Research—A Review |
| title_full_unstemmed | Optical Coherence Tomography Is a Promising Tool for Zebrafish-Based Research—A Review |
| title_short | Optical Coherence Tomography Is a Promising Tool for Zebrafish-Based Research—A Review |
| title_sort | optical coherence tomography is a promising tool for zebrafish based research a review |
| topic | zebrafish optical coherence tomography angiography polarization-sensitive multi-modal imaging pre-clinical biomedical research |
| url | https://www.mdpi.com/2306-5354/10/1/5 |
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