Huntington’s disease phenotypes are improved via mTORC1 modulation by small molecule therapy

Huntington’s disease phenotypes are improved via mTORC1 modulation by small molecule therapy

Show other versions (1)

Huntington’s Disease (HD) is a dominantly inherited neurodegenerative disease for which the major causes of mortality are neurodegeneration-associated aspiration pneumonia followed by cardiac failure. mTORC1 pathway perturbations are present in HD models and human tissues. Amelioration of mTORC1 def...

Full description

Bibliographic Details
Main Authors: Sophie St-Cyr, Daniel D. Child, Emilie Giaime, Alicia R. Smith, Christine J. Pascua, Seung Hahm, Eddine Saiah, Beverly L. Davidson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9423655/?tool=EBI

Similar Items

Similar Items