The Role of Sodium Glucose Cotransporter-2 Inhibitors in Atherosclerotic Cardiovascular Disease: A Narrative Review of Potential Mechanisms

The Role of Sodium Glucose Cotransporter-2 Inhibitors in Atherosclerotic Cardiovascular Disease: A Narrative Review of Potential Mechanisms

Sodium glucose cotransporter 2 (SGLT2) inhibitors are a class of medication with broad cardiovascular benefits in those with type 2 diabetes, chronic kidney disease, and heart failure. These include reductions in major adverse cardiac events and cardiovascular death. The mechanisms that underlie the...

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Bibliographic Details
Main Authors: Jennifer Y. Barraclough, Sanjay Patel, Jie Yu, Bruce Neal, Clare Arnott
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cells
Subjects:
sodium glucose cotransporter 2 inhibitor
atherosclerosis
cardiovascular disease
inflammation
mechanism of action
Online Access:https://www.mdpi.com/2073-4409/10/10/2699

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