Seasonal Malaria Chemoprevention with Sulphadoxine-Pyrimethamine and Amodiaquine Selects Pfdhfr-dhps Quintuple Mutant Genotype in Mali.

Seasonal Malaria Chemoprevention with Sulphadoxine-Pyrimethamine and Amodiaquine Selects Pfdhfr-dhps Quintuple Mutant Genotype in Mali.

Seasonal malaria chemoprevention (SMC) with sulphadoxine-pyrimethamine (SP) plus amodiaquine (AQ) is being scaled up in Sahelian countries of West Africa. However, the potential development of Plasmodium falciparum resistance to the respective component drugs is a major concern.Two cross-sectional s...

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Main Authors: Hamma Maiga, Estrella Lasry, Modibo Diarra, Issaka Sagara, Amadou Bamadio, Aliou Traore, Samba Coumare, Soma Bahonan, Boubou Sangare, Yeyia Dicko, Nouhoum Diallo, Aly Tembely, Djibril Traore, Hamidou Niangaly, François Dao, Aboubecrine Haidara, Alassane Dicko, Ogobara K Doumbo, Abdoulaye A Djimde
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5035027?pdf=render

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