Lung Surfactant and Its Use in Lung Diseases
The review considers the present views of lung surfactant (LS) functions with emphasis on its protective and barrier properties and ability to maintain local and adaptive immunity. The composition of commercial LS formulations is analyzed. Data on qualitative and quantitative LS abnormalities are pr...
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| Format: | Article |
| Language: | English |
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Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
2007-02-01
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| Series: | Общая реаниматология |
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| Online Access: | https://www.reanimatology.com/rmt/article/view/1089 |
| _version_ | 1797874386888294400 |
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| author | O. A. Rosenberg |
| author_facet | O. A. Rosenberg |
| author_sort | O. A. Rosenberg |
| collection | DOAJ |
| description | The review considers the present views of lung surfactant (LS) functions with emphasis on its protective and barrier properties and ability to maintain local and adaptive immunity. The composition of commercial LS formulations is analyzed. Data on qualitative and quantitative LS abnormalities are presented in various diseases in neonates and adults. The results of clinical trials of different LS formulations in the treatment of acute respiratory distress syndrome in adults are analyzed in detail. Recent data on the results of and prospects for surfactant therapy for bronchial asthma, chronic obstructive pulmonary disease and pulmonary tuberculosis are given. |
| first_indexed | 2024-04-10T01:30:07Z |
| format | Article |
| id | doaj.art-165a6858a37444609b2fb27db2b462ec |
| institution | Directory Open Access Journal |
| issn | 1813-9779 2411-7110 |
| language | English |
| last_indexed | 2024-04-10T01:30:07Z |
| publishDate | 2007-02-01 |
| publisher | Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia |
| record_format | Article |
| series | Общая реаниматология |
| spelling | doaj.art-165a6858a37444609b2fb27db2b462ec2023-03-13T09:32:47ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102007-02-0131667710.15360/1813-9779-2007-1-66-771089Lung Surfactant and Its Use in Lung DiseasesO. A. Rosenberg0Отдел медицинской биотехнологии Центрального научно-исследовательского рентгенорадиологического института Минздрава РФ, Санкт-ПетербургThe review considers the present views of lung surfactant (LS) functions with emphasis on its protective and barrier properties and ability to maintain local and adaptive immunity. The composition of commercial LS formulations is analyzed. Data on qualitative and quantitative LS abnormalities are presented in various diseases in neonates and adults. The results of clinical trials of different LS formulations in the treatment of acute respiratory distress syndrome in adults are analyzed in detail. Recent data on the results of and prospects for surfactant therapy for bronchial asthma, chronic obstructive pulmonary disease and pulmonary tuberculosis are given.https://www.reanimatology.com/rmt/article/view/1089легочный сурфактантпрепараты сурфактантасурфактант-терапияордсбронхиальная астмахоблтуберкулез |
| spellingShingle | O. A. Rosenberg Lung Surfactant and Its Use in Lung Diseases Общая реаниматология легочный сурфактант препараты сурфактанта сурфактант-терапия ордс бронхиальная астма хобл туберкулез |
| title | Lung Surfactant and Its Use in Lung Diseases |
| title_full | Lung Surfactant and Its Use in Lung Diseases |
| title_fullStr | Lung Surfactant and Its Use in Lung Diseases |
| title_full_unstemmed | Lung Surfactant and Its Use in Lung Diseases |
| title_short | Lung Surfactant and Its Use in Lung Diseases |
| title_sort | lung surfactant and its use in lung diseases |
| topic | легочный сурфактант препараты сурфактанта сурфактант-терапия ордс бронхиальная астма хобл туберкулез |
| url | https://www.reanimatology.com/rmt/article/view/1089 |
| work_keys_str_mv | AT oarosenberg lungsurfactantanditsuseinlungdiseases |