Caracterización clínica e histopatológica de la infección por Papiloma Virus humano de muestras de cérvix. Hospital Teodoro Maldonado Carbo “IESS”
Human Papilloma Virus (HPV) has a predilection for poly-stratified tissues, with persistence in the basal layers, hence mainly is the etiological agent of cervical cancer. Cervical cancer is the second most common cancer in women worldwide. HPV is unique oncogenic infectious agent that causes it....
| Main Authors: | , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Universidad Estatal de Milagro
2017-08-01
|
| Series: | Ciencia UNEMI |
| Subjects: | |
| Online Access: | http://ojs.unemi.edu.ec/index.php/cienciaunemi/article/view/502/394 |
| _version_ | 1811281327897444352 |
|---|---|
| author | Bedoya, César Sánchez-Giler, Sunny Zambrano, Dolores Herrera, Alan Silva, Alba Kuon-Yeng, Cristina Feliz, Emilio Vera, Carlos Mateo, Belén Sotomayor, Doménica Murillo, Juan- Pablo Marriot, Denisse Cevallos, Kerly Espinosa, Maylen España, Karol |
| author_facet | Bedoya, César Sánchez-Giler, Sunny Zambrano, Dolores Herrera, Alan Silva, Alba Kuon-Yeng, Cristina Feliz, Emilio Vera, Carlos Mateo, Belén Sotomayor, Doménica Murillo, Juan- Pablo Marriot, Denisse Cevallos, Kerly Espinosa, Maylen España, Karol |
| author_sort | Bedoya, César |
| collection | DOAJ |
| description | Human Papilloma Virus (HPV) has a predilection for poly-stratified tissues, with persistence in the basal layers, hence mainly is the
etiological agent of cervical cancer. Cervical cancer is the second most common cancer in women worldwide. HPV is unique oncogenic
infectious agent that causes it. The objective of the study was to determine the prevalence of the virus in women, using DNA detection
techniques through PCR, in real-time, from the cervical biopsy. In addition, the related histopathological and clinical characteristics
were established. The prevalence was 30.67%, the most frequently infected histopathology presentation was cervical and in situ
cancer. The more dysplastic the histopathology of the cervix, the more frequent the presentation of the virus. An association between
exposure to infection and the presence of whitish vaginal discharge and dyspareunia was demonstrated. |
| first_indexed | 2024-04-13T01:31:41Z |
| format | Article |
| id | doaj.art-165be80c68d248bcb5605d8a8e33b781 |
| institution | Directory Open Access Journal |
| issn | 1390-4272 2528-7737 |
| language | English |
| last_indexed | 2024-04-13T01:31:41Z |
| publishDate | 2017-08-01 |
| publisher | Universidad Estatal de Milagro |
| record_format | Article |
| series | Ciencia UNEMI |
| spelling | doaj.art-165be80c68d248bcb5605d8a8e33b7812022-12-22T03:08:30ZengUniversidad Estatal de MilagroCiencia UNEMI1390-42722528-77372017-08-011023105111Caracterización clínica e histopatológica de la infección por Papiloma Virus humano de muestras de cérvix. Hospital Teodoro Maldonado Carbo “IESS”Bedoya, César0Sánchez-Giler, Sunny1Zambrano, Dolores2Herrera, Alan3Silva, Alba4Kuon-Yeng, Cristina5Feliz, Emilio6Vera, Carlos7Mateo, Belén8Sotomayor, Doménica9Murillo, Juan- Pablo10Marriot, Denisse11Cevallos, Kerly12Espinosa, Maylen13España, Karol14 Instituto Nacional de Investigaciones en Salud Pública, Escuela Superior Politécnica del Litoral Universidad Espíritu Santo Universidad Espíritu Santo Universidad Espíritu Santo Universidad Espíritu Santo Universidad Espíritu Santo Universidad Espíritu Santo Universidad Espíritu Santo Universidad Espíritu Santo Universidad Espíritu Santo Universidad Espíritu Santo Universidad Espíritu Santo Universidad Espíritu Santo Instituto Nacional de Investigaciones en Salud Pública Instituto Nacional de Investigaciones en Salud PúblicaHuman Papilloma Virus (HPV) has a predilection for poly-stratified tissues, with persistence in the basal layers, hence mainly is the etiological agent of cervical cancer. Cervical cancer is the second most common cancer in women worldwide. HPV is unique oncogenic infectious agent that causes it. The objective of the study was to determine the prevalence of the virus in women, using DNA detection techniques through PCR, in real-time, from the cervical biopsy. In addition, the related histopathological and clinical characteristics were established. The prevalence was 30.67%, the most frequently infected histopathology presentation was cervical and in situ cancer. The more dysplastic the histopathology of the cervix, the more frequent the presentation of the virus. An association between exposure to infection and the presence of whitish vaginal discharge and dyspareunia was demonstrated.http://ojs.unemi.edu.ec/index.php/cienciaunemi/article/view/502/394cancercervixL1 geneHuman Papilloma Virusconserved regions |
| spellingShingle | Bedoya, César Sánchez-Giler, Sunny Zambrano, Dolores Herrera, Alan Silva, Alba Kuon-Yeng, Cristina Feliz, Emilio Vera, Carlos Mateo, Belén Sotomayor, Doménica Murillo, Juan- Pablo Marriot, Denisse Cevallos, Kerly Espinosa, Maylen España, Karol Caracterización clínica e histopatológica de la infección por Papiloma Virus humano de muestras de cérvix. Hospital Teodoro Maldonado Carbo “IESS” Ciencia UNEMI cancer cervix L1 gene Human Papilloma Virus conserved regions |
| title | Caracterización clínica e histopatológica de la infección por Papiloma Virus humano de muestras de cérvix. Hospital Teodoro Maldonado Carbo “IESS” |
| title_full | Caracterización clínica e histopatológica de la infección por Papiloma Virus humano de muestras de cérvix. Hospital Teodoro Maldonado Carbo “IESS” |
| title_fullStr | Caracterización clínica e histopatológica de la infección por Papiloma Virus humano de muestras de cérvix. Hospital Teodoro Maldonado Carbo “IESS” |
| title_full_unstemmed | Caracterización clínica e histopatológica de la infección por Papiloma Virus humano de muestras de cérvix. Hospital Teodoro Maldonado Carbo “IESS” |
| title_short | Caracterización clínica e histopatológica de la infección por Papiloma Virus humano de muestras de cérvix. Hospital Teodoro Maldonado Carbo “IESS” |
| title_sort | caracterizacion clinica e histopatologica de la infeccion por papiloma virus humano de muestras de cervix hospital teodoro maldonado carbo iess |
| topic | cancer cervix L1 gene Human Papilloma Virus conserved regions |
| url | http://ojs.unemi.edu.ec/index.php/cienciaunemi/article/view/502/394 |
| work_keys_str_mv | AT bedoyacesar caracterizacionclinicaehistopatologicadelainfeccionporpapilomavirushumanodemuestrasdecervixhospitalteodoromaldonadocarboiess AT sanchezgilersunny caracterizacionclinicaehistopatologicadelainfeccionporpapilomavirushumanodemuestrasdecervixhospitalteodoromaldonadocarboiess AT zambranodolores caracterizacionclinicaehistopatologicadelainfeccionporpapilomavirushumanodemuestrasdecervixhospitalteodoromaldonadocarboiess AT herreraalan caracterizacionclinicaehistopatologicadelainfeccionporpapilomavirushumanodemuestrasdecervixhospitalteodoromaldonadocarboiess AT silvaalba caracterizacionclinicaehistopatologicadelainfeccionporpapilomavirushumanodemuestrasdecervixhospitalteodoromaldonadocarboiess AT kuonyengcristina caracterizacionclinicaehistopatologicadelainfeccionporpapilomavirushumanodemuestrasdecervixhospitalteodoromaldonadocarboiess AT felizemilio caracterizacionclinicaehistopatologicadelainfeccionporpapilomavirushumanodemuestrasdecervixhospitalteodoromaldonadocarboiess AT veracarlos caracterizacionclinicaehistopatologicadelainfeccionporpapilomavirushumanodemuestrasdecervixhospitalteodoromaldonadocarboiess AT mateobelen caracterizacionclinicaehistopatologicadelainfeccionporpapilomavirushumanodemuestrasdecervixhospitalteodoromaldonadocarboiess AT sotomayordomenica caracterizacionclinicaehistopatologicadelainfeccionporpapilomavirushumanodemuestrasdecervixhospitalteodoromaldonadocarboiess AT murillojuanpablo caracterizacionclinicaehistopatologicadelainfeccionporpapilomavirushumanodemuestrasdecervixhospitalteodoromaldonadocarboiess AT marriotdenisse caracterizacionclinicaehistopatologicadelainfeccionporpapilomavirushumanodemuestrasdecervixhospitalteodoromaldonadocarboiess AT cevalloskerly caracterizacionclinicaehistopatologicadelainfeccionporpapilomavirushumanodemuestrasdecervixhospitalteodoromaldonadocarboiess AT espinosamaylen caracterizacionclinicaehistopatologicadelainfeccionporpapilomavirushumanodemuestrasdecervixhospitalteodoromaldonadocarboiess AT espanakarol caracterizacionclinicaehistopatologicadelainfeccionporpapilomavirushumanodemuestrasdecervixhospitalteodoromaldonadocarboiess |