The Historical Use of Radiotherapy in the Treatment of Sinus Infections

The aim of this paper is to assess the historical role of radiotherapy in the treatment of sinus infections. This assessment involved a literature-based review of how radiotherapy was used to treat sinus infections in the first half of the 20 th century. Low doses of x-rays were used with considerab...

Full description

Bibliographic Details
Main Authors: Edward J. Calabrese Ph.D., Gaurav Dhawan MPH
Format: Article
Language:English
Published: SAGE Publishing 2013-10-01
Series:Dose-Response
Online Access:https://doi.org/10.2203/dose-response.13-004.Calabrese
_version_ 1818157025213808640
author Edward J. Calabrese Ph.D.
Gaurav Dhawan MPH
author_facet Edward J. Calabrese Ph.D.
Gaurav Dhawan MPH
author_sort Edward J. Calabrese Ph.D.
collection DOAJ
description The aim of this paper is to assess the historical role of radiotherapy in the treatment of sinus infections. This assessment involved a literature-based review of how radiotherapy was used to treat sinus infections in the first half of the 20 th century. Low doses of x-rays were used with considerable success to treat nearly 3,000 patients of sinus infection in a span of 12 years with these cases being reported in leading medical journals as case studies. The mechanism of x-ray induced reduction of inflammation and increased tissue repair is uncertain but appears to be related to the development of a multifactorial and integrative anti-inflammatory phenotype.
first_indexed 2024-12-11T15:07:38Z
format Article
id doaj.art-165d6b7028034fc3b625ada57967abea
institution Directory Open Access Journal
issn 1559-3258
language English
last_indexed 2024-12-11T15:07:38Z
publishDate 2013-10-01
publisher SAGE Publishing
record_format Article
series Dose-Response
spelling doaj.art-165d6b7028034fc3b625ada57967abea2022-12-22T01:00:50ZengSAGE PublishingDose-Response1559-32582013-10-011110.2203/dose-response.13-004.CalabreseThe Historical Use of Radiotherapy in the Treatment of Sinus InfectionsEdward J. Calabrese Ph.D.Gaurav Dhawan MPHThe aim of this paper is to assess the historical role of radiotherapy in the treatment of sinus infections. This assessment involved a literature-based review of how radiotherapy was used to treat sinus infections in the first half of the 20 th century. Low doses of x-rays were used with considerable success to treat nearly 3,000 patients of sinus infection in a span of 12 years with these cases being reported in leading medical journals as case studies. The mechanism of x-ray induced reduction of inflammation and increased tissue repair is uncertain but appears to be related to the development of a multifactorial and integrative anti-inflammatory phenotype.https://doi.org/10.2203/dose-response.13-004.Calabrese
spellingShingle Edward J. Calabrese Ph.D.
Gaurav Dhawan MPH
The Historical Use of Radiotherapy in the Treatment of Sinus Infections
Dose-Response
title The Historical Use of Radiotherapy in the Treatment of Sinus Infections
title_full The Historical Use of Radiotherapy in the Treatment of Sinus Infections
title_fullStr The Historical Use of Radiotherapy in the Treatment of Sinus Infections
title_full_unstemmed The Historical Use of Radiotherapy in the Treatment of Sinus Infections
title_short The Historical Use of Radiotherapy in the Treatment of Sinus Infections
title_sort historical use of radiotherapy in the treatment of sinus infections
url https://doi.org/10.2203/dose-response.13-004.Calabrese
work_keys_str_mv AT edwardjcalabresephd thehistoricaluseofradiotherapyinthetreatmentofsinusinfections
AT gauravdhawanmph thehistoricaluseofradiotherapyinthetreatmentofsinusinfections
AT edwardjcalabresephd historicaluseofradiotherapyinthetreatmentofsinusinfections
AT gauravdhawanmph historicaluseofradiotherapyinthetreatmentofsinusinfections