Dietary sucrose is essential to the development of liver injury in the methionine-choline-deficient model of steatohepatitis[S]

Dietary sucrose is essential to the development of liver injury in the methionine-choline-deficient model of steatohepatitis[S]

Methionine-choline-deficient (MCD) diets cause steatohepatitis in rodents and are used to study the pathophysiology of fatty liver disease in human beings. The most widely used commercial MCD formulas not only lack methionine and choline but also contain excess sucrose and fat. The objective of this...

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Bibliographic Details
Main Authors:	Michael K. Pickens, Jim S. Yan, Raymond K. Ng, Hisanobu Ogata, James P. Grenert, Carine Beysen, Scott M. Turner, Jacquelyn J. Maher
Format:	Article
Language:	English
Published:	Elsevier 2009-10-01
Series:	Journal of Lipid Research
Subjects:	fatty acid fatty liver apoptosis de novo lipogenesis
Online Access:	http://www.sciencedirect.com/science/article/pii/S002222752030715X

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