Rapid Cerebral Metabolic Shift during Neonatal Sepsis Is Attenuated by Enteral Colostrum Supplementation in Preterm Pigs

Rapid Cerebral Metabolic Shift during Neonatal Sepsis Is Attenuated by Enteral Colostrum Supplementation in Preterm Pigs

Sepsis, the clinical manifestation of serious infection, may disturb normal brain development, especially in preterm infants with an immature brain. We hypothesized that neonatal sepsis induces systemic metabolic alterations that rapidly affect metabolic signatures in immature brain and cerebrospina...

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Bibliographic Details
Main Authors: Masoumeh Alinaghi, Ping-Ping Jiang, Anders Brunse, Per Torp Sangild, Hanne Christine Bertram
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Metabolites
Subjects:
NMR metabolomics
neonatal sepsis
preterm infants
bloodstream infection
cerebrospinal fluid
Staphylococcus epidermidis
brain metabolites
cerebral metabolism
enteral feeding
bioactive dairy components
Online Access:http://www.mdpi.com/2218-1989/9/1/13

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