Monocytes Exposed to Immune Complexes Reduce pDC Type 1 Interferon Response to Vidutolimod

Monocytes Exposed to Immune Complexes Reduce pDC Type 1 Interferon Response to Vidutolimod

Vidutolimod, also known as CMP-001, is a virus-like particle composed of the Qβ bacteriophage coat protein encasing a TLR9 agonist. Vidutolimod injected intratumorally is showing promise in early phase clinical trials based on its ability to alter the tumor microenvironment and induce an anti-tumor...

Full description

Bibliographic Details
Main Authors: Shakoora A. Sabree, Caitlin D. Lemke-Miltner, Sue E. Blackwell, Chaobo Yin, Aaron Bossler, Kareem Ebeid, Aliasger K. Salem, George J. Weiner
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Vaccines
Subjects:
vidutolimod
Fc gamma receptor
TLR9
pDCs
Type 1 Interferon
monocytes
Online Access:https://www.mdpi.com/2076-393X/9/9/982

Similar Items

Similar Items