Enteropathogenic <i>Yersinia</i> with Public Health Relevance Found in Dogs and Cats in Finland
Yersiniosis is a common zoonotic enteric disease among humans, which has been linked to pigs and contaminated food, especially pork. The epidemiology of yersiniosis is still obscure, and studies on yersiniosis in pets are very scarce. In this study, we performed pheno- and genotypic characterisation...
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MDPI AG
2024-01-01
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| Series: | Pathogens |
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| Online Access: | https://www.mdpi.com/2076-0817/13/1/54 |
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| author | Maria Fredriksson-Ahomaa Thomas Grönthal Viivi Heljanko Venla Johansson Merja Rantala Annamari Heikinheimo Riikka Laukkanen-Ninios |
| author_facet | Maria Fredriksson-Ahomaa Thomas Grönthal Viivi Heljanko Venla Johansson Merja Rantala Annamari Heikinheimo Riikka Laukkanen-Ninios |
| author_sort | Maria Fredriksson-Ahomaa |
| collection | DOAJ |
| description | Yersiniosis is a common zoonotic enteric disease among humans, which has been linked to pigs and contaminated food, especially pork. The epidemiology of yersiniosis is still obscure, and studies on yersiniosis in pets are very scarce. In this study, we performed pheno- and genotypic characterisation of 50 <i>Yersinia</i> strains isolated from pets in Finland between 2012 and 2023. <i>Y. enterocolitica</i> 4/O:3/ST135, the most common type in human yersiniosis, was also the most common type (68%) found in clinical faecal samples in our study. Also, human pathogenic <i>Y. enterocolitica</i> 2/O:9/ST139 and <i>Y. pseudotuberculosis</i> O:1/ST9 and O:1/ST42 strains carrying all essential pathogenic genes were identified. Three <i>Y. enterocolitica</i> 4/O:3/ST9 strains were multi-drug-resistant and two of them were highly related, showing one allelic difference (AD) with core genome multi-locus sequence typing. Non-pathogenic, genotypically highly diverse <i>Y. enterocolitica</i> 1A strains, showing more than 1000 ADs and missing the essential virulence genes, were also recognised in dogs and cats. Our study demonstrates that pets can excrete human pathogenic <i>Yersinia</i> in their faeces and may serve as an infection source for human yersiniosis, especially in families with small children in close contact with their pets. |
| first_indexed | 2024-03-08T10:38:05Z |
| format | Article |
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| institution | Directory Open Access Journal |
| issn | 2076-0817 |
| language | English |
| last_indexed | 2024-03-08T10:38:05Z |
| publishDate | 2024-01-01 |
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| record_format | Article |
| series | Pathogens |
| spelling | doaj.art-16721e6f0724490496b4182986f2d4ae2024-01-26T18:03:41ZengMDPI AGPathogens2076-08172024-01-011315410.3390/pathogens13010054Enteropathogenic <i>Yersinia</i> with Public Health Relevance Found in Dogs and Cats in FinlandMaria Fredriksson-Ahomaa0Thomas Grönthal1Viivi Heljanko2Venla Johansson3Merja Rantala4Annamari Heikinheimo5Riikka Laukkanen-Ninios6Department of Food Hygiene and Environmental Hygiene, Faculty of Veterinary Medicine, University of Helsinki, P.O. Box 66, 00014 Helsinki, FinlandAnimal Health Diagnostic Unit, Finnish Food Authority, Mustialankatu 3, 00790 Helsinki, FinlandDepartment of Food Hygiene and Environmental Hygiene, Faculty of Veterinary Medicine, University of Helsinki, P.O. Box 66, 00014 Helsinki, FinlandDepartment of Food Hygiene and Environmental Hygiene, Faculty of Veterinary Medicine, University of Helsinki, P.O. Box 66, 00014 Helsinki, FinlandDepartment of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, P.O. Box 57, 00014 Helsinki, FinlandDepartment of Food Hygiene and Environmental Hygiene, Faculty of Veterinary Medicine, University of Helsinki, P.O. Box 66, 00014 Helsinki, FinlandDepartment of Food Hygiene and Environmental Hygiene, Faculty of Veterinary Medicine, University of Helsinki, P.O. Box 66, 00014 Helsinki, FinlandYersiniosis is a common zoonotic enteric disease among humans, which has been linked to pigs and contaminated food, especially pork. The epidemiology of yersiniosis is still obscure, and studies on yersiniosis in pets are very scarce. In this study, we performed pheno- and genotypic characterisation of 50 <i>Yersinia</i> strains isolated from pets in Finland between 2012 and 2023. <i>Y. enterocolitica</i> 4/O:3/ST135, the most common type in human yersiniosis, was also the most common type (68%) found in clinical faecal samples in our study. Also, human pathogenic <i>Y. enterocolitica</i> 2/O:9/ST139 and <i>Y. pseudotuberculosis</i> O:1/ST9 and O:1/ST42 strains carrying all essential pathogenic genes were identified. Three <i>Y. enterocolitica</i> 4/O:3/ST9 strains were multi-drug-resistant and two of them were highly related, showing one allelic difference (AD) with core genome multi-locus sequence typing. Non-pathogenic, genotypically highly diverse <i>Y. enterocolitica</i> 1A strains, showing more than 1000 ADs and missing the essential virulence genes, were also recognised in dogs and cats. Our study demonstrates that pets can excrete human pathogenic <i>Yersinia</i> in their faeces and may serve as an infection source for human yersiniosis, especially in families with small children in close contact with their pets.https://www.mdpi.com/2076-0817/13/1/54<i>Yersinia enterocolitica</i><i>Yersinia pseudotuberculosis</i>petsvirulenceresistancecharacteristics |
| spellingShingle | Maria Fredriksson-Ahomaa Thomas Grönthal Viivi Heljanko Venla Johansson Merja Rantala Annamari Heikinheimo Riikka Laukkanen-Ninios Enteropathogenic <i>Yersinia</i> with Public Health Relevance Found in Dogs and Cats in Finland Pathogens <i>Yersinia enterocolitica</i> <i>Yersinia pseudotuberculosis</i> pets virulence resistance characteristics |
| title | Enteropathogenic <i>Yersinia</i> with Public Health Relevance Found in Dogs and Cats in Finland |
| title_full | Enteropathogenic <i>Yersinia</i> with Public Health Relevance Found in Dogs and Cats in Finland |
| title_fullStr | Enteropathogenic <i>Yersinia</i> with Public Health Relevance Found in Dogs and Cats in Finland |
| title_full_unstemmed | Enteropathogenic <i>Yersinia</i> with Public Health Relevance Found in Dogs and Cats in Finland |
| title_short | Enteropathogenic <i>Yersinia</i> with Public Health Relevance Found in Dogs and Cats in Finland |
| title_sort | enteropathogenic i yersinia i with public health relevance found in dogs and cats in finland |
| topic | <i>Yersinia enterocolitica</i> <i>Yersinia pseudotuberculosis</i> pets virulence resistance characteristics |
| url | https://www.mdpi.com/2076-0817/13/1/54 |
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