Microglia-Specific Expression of HEXA and HEXB Leads to Poor Prognosis in Glioblastoma Patients

Microglia-Specific Expression of HEXA and HEXB Leads to Poor Prognosis in Glioblastoma Patients

Glioblastoma multiforme (GBM) is one of the deadliest cancers in brain. There have been few treatment advances for GBM despite increasing scientific understanding of this disease. β-hexosaminidase (Hex) is an important enzyme system in human body, encoded by two genes, HEXA and HEXB, are closely rel...

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Bibliographic Details
Main Authors: Mengxian Jia, Wenbin Zhang, Junle Zhu, Changgang Huang, Jian Zhou, Jiashu Lian, Ying Wang, Honglin Teng, Zhihui Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Oncology
Subjects:
glioblastoma
microglia
HEXA
HEXB
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.685893/full

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