Isolation and Structure Elucidation of a Novel Symmetrical Macrocyclic Phthalate Hexaester

A novel symmetrical macrocyclic phthalate hexaester (<b>1</b>) and a known macrocyclic phthalate tetraester (<b>2</b>) were isolated during a natural product-exploring program on the cyanobacterium <i>Moorea producens</i>. Their structures were elucidated based on...

Full description

Bibliographic Details
Main Authors: Michiya Kamio, Weina Jiang, Hiroki Osada, Masayuki Fukuoka, Hajime Uchida, Ryuichi Watanabe, Toshiyuki Suzuki, Hiroshi Nagai
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Symmetry
Subjects:
Online Access:https://www.mdpi.com/2073-8994/13/2/361
_version_ 1797395552207372288
author Michiya Kamio
Weina Jiang
Hiroki Osada
Masayuki Fukuoka
Hajime Uchida
Ryuichi Watanabe
Toshiyuki Suzuki
Hiroshi Nagai
author_facet Michiya Kamio
Weina Jiang
Hiroki Osada
Masayuki Fukuoka
Hajime Uchida
Ryuichi Watanabe
Toshiyuki Suzuki
Hiroshi Nagai
author_sort Michiya Kamio
collection DOAJ
description A novel symmetrical macrocyclic phthalate hexaester (<b>1</b>) and a known macrocyclic phthalate tetraester (<b>2</b>) were isolated during a natural product-exploring program on the cyanobacterium <i>Moorea producens</i>. Their structures were elucidated based on spectroscopic data, including nuclear magnetic resonance and high-resolution mass spectra. In the antibacterial activity test, compounds <b>1</b> and <b>2</b> showed no bioactivity at the concentrations tested.
first_indexed 2024-03-09T00:36:10Z
format Article
id doaj.art-16750adaf05c4da3b5f45d59104143d0
institution Directory Open Access Journal
issn 2073-8994
language English
last_indexed 2024-03-09T00:36:10Z
publishDate 2021-02-01
publisher MDPI AG
record_format Article
series Symmetry
spelling doaj.art-16750adaf05c4da3b5f45d59104143d02023-12-11T18:07:08ZengMDPI AGSymmetry2073-89942021-02-0113236110.3390/sym13020361Isolation and Structure Elucidation of a Novel Symmetrical Macrocyclic Phthalate HexaesterMichiya Kamio0Weina Jiang1Hiroki Osada2Masayuki Fukuoka3Hajime Uchida4Ryuichi Watanabe5Toshiyuki Suzuki6Hiroshi Nagai7Department of Ocean Sciences, Tokyo University of Marine Science and Technology, Tokyo 108-8477, JapanDepartment of Ocean Sciences, Tokyo University of Marine Science and Technology, Tokyo 108-8477, JapanDepartment of Ocean Sciences, Tokyo University of Marine Science and Technology, Tokyo 108-8477, JapanDepartment of Ocean Sciences, Tokyo University of Marine Science and Technology, Tokyo 108-8477, JapanFisheries Technology Institute, Japan Fisheries Research and Education Agency, Yokohama 236-8648, JapanFisheries Technology Institute, Japan Fisheries Research and Education Agency, Yokohama 236-8648, JapanFisheries Technology Institute, Japan Fisheries Research and Education Agency, Yokohama 236-8648, JapanDepartment of Ocean Sciences, Tokyo University of Marine Science and Technology, Tokyo 108-8477, JapanA novel symmetrical macrocyclic phthalate hexaester (<b>1</b>) and a known macrocyclic phthalate tetraester (<b>2</b>) were isolated during a natural product-exploring program on the cyanobacterium <i>Moorea producens</i>. Their structures were elucidated based on spectroscopic data, including nuclear magnetic resonance and high-resolution mass spectra. In the antibacterial activity test, compounds <b>1</b> and <b>2</b> showed no bioactivity at the concentrations tested.https://www.mdpi.com/2073-8994/13/2/361phthalate estercyanobacterium<i>Moorea producens</i>isolationstructural elucidation
spellingShingle Michiya Kamio
Weina Jiang
Hiroki Osada
Masayuki Fukuoka
Hajime Uchida
Ryuichi Watanabe
Toshiyuki Suzuki
Hiroshi Nagai
Isolation and Structure Elucidation of a Novel Symmetrical Macrocyclic Phthalate Hexaester
Symmetry
phthalate ester
cyanobacterium
<i>Moorea producens</i>
isolation
structural elucidation
title Isolation and Structure Elucidation of a Novel Symmetrical Macrocyclic Phthalate Hexaester
title_full Isolation and Structure Elucidation of a Novel Symmetrical Macrocyclic Phthalate Hexaester
title_fullStr Isolation and Structure Elucidation of a Novel Symmetrical Macrocyclic Phthalate Hexaester
title_full_unstemmed Isolation and Structure Elucidation of a Novel Symmetrical Macrocyclic Phthalate Hexaester
title_short Isolation and Structure Elucidation of a Novel Symmetrical Macrocyclic Phthalate Hexaester
title_sort isolation and structure elucidation of a novel symmetrical macrocyclic phthalate hexaester
topic phthalate ester
cyanobacterium
<i>Moorea producens</i>
isolation
structural elucidation
url https://www.mdpi.com/2073-8994/13/2/361
work_keys_str_mv AT michiyakamio isolationandstructureelucidationofanovelsymmetricalmacrocyclicphthalatehexaester
AT weinajiang isolationandstructureelucidationofanovelsymmetricalmacrocyclicphthalatehexaester
AT hirokiosada isolationandstructureelucidationofanovelsymmetricalmacrocyclicphthalatehexaester
AT masayukifukuoka isolationandstructureelucidationofanovelsymmetricalmacrocyclicphthalatehexaester
AT hajimeuchida isolationandstructureelucidationofanovelsymmetricalmacrocyclicphthalatehexaester
AT ryuichiwatanabe isolationandstructureelucidationofanovelsymmetricalmacrocyclicphthalatehexaester
AT toshiyukisuzuki isolationandstructureelucidationofanovelsymmetricalmacrocyclicphthalatehexaester
AT hiroshinagai isolationandstructureelucidationofanovelsymmetricalmacrocyclicphthalatehexaester