Mitochondrial Reactive Oxygen Species, Insulin Resistance, and Nrf2-Mediated Oxidative Stress Response—Toward an Actionable Strategy for Anti-Aging

Mitochondrial Reactive Oxygen Species, Insulin Resistance, and Nrf2-Mediated Oxidative Stress Response—Toward an Actionable Strategy for Anti-Aging

Reactive oxygen species (ROS) are produced mainly by mitochondrial respiration and function as signaling molecules in the physiological range. However, ROS production is also associated with the pathogenesis of various diseases, including insulin resistance (IR) and type 2 diabetes (T2D). This revie...

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Bibliographic Details
Main Authors: Shuya Kasai, Daichi Kokubu, Hiroki Mizukami, Ken Itoh
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Biomolecules
Subjects:
mitochondrial ROS
Nrf2
insulin resistance
diabetes
adipose tissue
Online Access:https://www.mdpi.com/2218-273X/13/10/1544

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