COMPARATIVE ANALYSIS OF COLON PREPARATION USING POLY ETHYLENE GLYCOL (PEG) WITH LACTULOSE FOR COLONOSCOPY
Objective: To compare the adequacy of preparation for colonoscopy using polyethylene glycol with lactulose. Study Design: Quasi experimental study. Place and Duration of Study: Department of Gastroenterology, Combined Military Hospital Lahore, from Jul 2019 to Dec 2019. Methodology: The enr...
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| Format: | Article |
| Language: | English |
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Army Medical College Rawalpindi
2020-10-01
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| Series: | Pakistan Armed Forces Medical Journal |
| Subjects: | |
| Online Access: | https://www.pafmj.org/index.php/PAFMJ/article/view/5546/2949 |
| _version_ | 1818731592298790912 |
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| author | Asma Asghar Laima Alam Asif Farooq Arshad Hayat Farrukh Saeed Jehangir Ahmed |
| author_facet | Asma Asghar Laima Alam Asif Farooq Arshad Hayat Farrukh Saeed Jehangir Ahmed |
| author_sort | Asma Asghar |
| collection | DOAJ |
| description | Objective: To compare the adequacy of preparation for colonoscopy using polyethylene glycol with lactulose.
Study Design: Quasi experimental study.
Place and Duration of Study: Department of Gastroenterology, Combined Military Hospital Lahore, from Jul 2019 to Dec 2019.
Methodology: The enrolled patients were randomized into two equal groups. Group A received polyethylene glycol (PEG) formulation containing 13.125g x 24 sachets with 4 liters of water over 24 hours, group B received lactulose 600ml (66.7g/100ml) with 4 liters of water over 24 hours. Quality of bowel preparation was assessed using Ottawa scoring system (OBPS). A designed questionnaire was used for recording patients’ tolerability toward the preparation method. Questionnaire was filled pre and post-procedure for socio-demographic data and scores. Patients were also assessed for tolerability of procedure and palatability of the solutions by questionnaire.
Results: The median age of patients in group A was 49 (26 IQR) years and in group B was 48 (18.5 IQR) years. Out of 100 patients 60% were males and 40% were females. The most common indication of colonoscopy was anemia (32%), followed by diarrhea (26%), bleeding per-rectum (24%) and constipation (18%). Polyethylene glycol showed better bowel cleansing score compared with lactulose (p<0.001). Tolerability and palatability for polyethylene glycol were statistically superior to the same volume of lactulose.
Conclusion: Polyethylene glycol is superior to lactulose in terms of bowel preparation, tolerability and palatability. |
| first_indexed | 2024-12-17T23:20:07Z |
| format | Article |
| id | doaj.art-16794adc05da47d9a7494d5ba0babac6 |
| institution | Directory Open Access Journal |
| issn | 0030-9648 2411-8842 |
| language | English |
| last_indexed | 2024-12-17T23:20:07Z |
| publishDate | 2020-10-01 |
| publisher | Army Medical College Rawalpindi |
| record_format | Article |
| series | Pakistan Armed Forces Medical Journal |
| spelling | doaj.art-16794adc05da47d9a7494d5ba0babac62022-12-21T21:28:54ZengArmy Medical College RawalpindiPakistan Armed Forces Medical Journal0030-96482411-88422020-10-0170512611265COMPARATIVE ANALYSIS OF COLON PREPARATION USING POLY ETHYLENE GLYCOL (PEG) WITH LACTULOSE FOR COLONOSCOPYAsma Asghar0Laima Alam1Asif Farooq2Arshad Hayat3Farrukh Saeed4Jehangir Ahmed5Combined Military Hospital Lahore/National University of Medical Sciences (NUMS) PakistanBahria Town International Hospital, Rawalpindi PakistanCombined Military Hospital Lahore/National University of Medical Sciences (NUMS) PakistanCombined Military Hospital Lahore/National University of Medical Sciences (NUMS) PakistanPak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi PakistanPerveen Akhtar Hospital, Kotli PakistanObjective: To compare the adequacy of preparation for colonoscopy using polyethylene glycol with lactulose. Study Design: Quasi experimental study. Place and Duration of Study: Department of Gastroenterology, Combined Military Hospital Lahore, from Jul 2019 to Dec 2019. Methodology: The enrolled patients were randomized into two equal groups. Group A received polyethylene glycol (PEG) formulation containing 13.125g x 24 sachets with 4 liters of water over 24 hours, group B received lactulose 600ml (66.7g/100ml) with 4 liters of water over 24 hours. Quality of bowel preparation was assessed using Ottawa scoring system (OBPS). A designed questionnaire was used for recording patients’ tolerability toward the preparation method. Questionnaire was filled pre and post-procedure for socio-demographic data and scores. Patients were also assessed for tolerability of procedure and palatability of the solutions by questionnaire. Results: The median age of patients in group A was 49 (26 IQR) years and in group B was 48 (18.5 IQR) years. Out of 100 patients 60% were males and 40% were females. The most common indication of colonoscopy was anemia (32%), followed by diarrhea (26%), bleeding per-rectum (24%) and constipation (18%). Polyethylene glycol showed better bowel cleansing score compared with lactulose (p<0.001). Tolerability and palatability for polyethylene glycol were statistically superior to the same volume of lactulose. Conclusion: Polyethylene glycol is superior to lactulose in terms of bowel preparation, tolerability and palatability.https://www.pafmj.org/index.php/PAFMJ/article/view/5546/2949bowel preparationcolonoscopylactuloseottawa score |
| spellingShingle | Asma Asghar Laima Alam Asif Farooq Arshad Hayat Farrukh Saeed Jehangir Ahmed COMPARATIVE ANALYSIS OF COLON PREPARATION USING POLY ETHYLENE GLYCOL (PEG) WITH LACTULOSE FOR COLONOSCOPY Pakistan Armed Forces Medical Journal bowel preparation colonoscopy lactulose ottawa score |
| title | COMPARATIVE ANALYSIS OF COLON PREPARATION USING POLY ETHYLENE GLYCOL (PEG) WITH LACTULOSE FOR COLONOSCOPY |
| title_full | COMPARATIVE ANALYSIS OF COLON PREPARATION USING POLY ETHYLENE GLYCOL (PEG) WITH LACTULOSE FOR COLONOSCOPY |
| title_fullStr | COMPARATIVE ANALYSIS OF COLON PREPARATION USING POLY ETHYLENE GLYCOL (PEG) WITH LACTULOSE FOR COLONOSCOPY |
| title_full_unstemmed | COMPARATIVE ANALYSIS OF COLON PREPARATION USING POLY ETHYLENE GLYCOL (PEG) WITH LACTULOSE FOR COLONOSCOPY |
| title_short | COMPARATIVE ANALYSIS OF COLON PREPARATION USING POLY ETHYLENE GLYCOL (PEG) WITH LACTULOSE FOR COLONOSCOPY |
| title_sort | comparative analysis of colon preparation using poly ethylene glycol peg with lactulose for colonoscopy |
| topic | bowel preparation colonoscopy lactulose ottawa score |
| url | https://www.pafmj.org/index.php/PAFMJ/article/view/5546/2949 |
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