Interaction between the 5-HT system and the basal ganglia: Functional implication and therapeutic perspective in Parkinson’s disease

Interaction between the 5-HT system and the basal ganglia: Functional implication and therapeutic perspective in Parkinson’s disease

The neurotransmitter serotonin (5-HT) has a multifaceted function in the modulation of information processing through the activation of multiple receptor families, including G-protein-coupled receptor subtypes (5-HT1, 5-HT2, 5-HT4-7) and ligand-gated ion channels (5-HT3). The largest population of s...

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Bibliographic Details
Main Authors: Cristina eMiguelez, Teresa eMorera-Herreras, Maria eTorrecilla, Jose Angel eRuiz-Ortega, Luisa eUgedo
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-03-01
Series:Frontiers in Neural Circuits
Subjects:
Basal Ganglia
Electrophysiology
Parkinson’s disease
5-HT
L-DOPA induced dyskinesia
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncir.2014.00021/full

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