Cerebrovascular disorders associated with agenesis of the internal carotid artery: Findings on digital subtraction angiography
ObjectiveAgenesis of the internal carotid artery (ICA) is a rare vascular condition that is complicated by intracranial aneurysms and rete mirabile. The altered hemodynamics caused by this distinctive cerebrovascular angioarchitecture can cause ischemic or hemorrhagic accidents. Data on clinical and...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-11-01
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| Series: | Frontiers in Surgery |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fsurg.2022.953697/full |
| _version_ | 1811223768149786624 |
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| author | Xiaolong Xu Hongjian Shen Hongyu Ma Xiaoxi Zhang Lei Zhang Qiang Li Rui Zhao Dongwei Dai Zifu Li Pengfei Yang Jianmin Liu |
| author_facet | Xiaolong Xu Hongjian Shen Hongyu Ma Xiaoxi Zhang Lei Zhang Qiang Li Rui Zhao Dongwei Dai Zifu Li Pengfei Yang Jianmin Liu |
| author_sort | Xiaolong Xu |
| collection | DOAJ |
| description | ObjectiveAgenesis of the internal carotid artery (ICA) is a rare vascular condition that is complicated by intracranial aneurysms and rete mirabile. The altered hemodynamics caused by this distinctive cerebrovascular angioarchitecture can cause ischemic or hemorrhagic accidents. Data on clinical and radiographic features have been limited to describing this vascular pattern. We present five cases of agenesis of the internal carotid artery confirmed by digital subtraction angiography (DSA) and further investigate the influence of altered angioarchitecture on the integrity of intracranial morphology.MethodsCases of ICA anomalies were screened from the patients who underwent DSA in two hospitals. Clinical manifestation, radiographic features, management, and outcomes were retrospectively reviewed.ResultsFive patients [mean age 44 years (range, 30–65 years)] were included. Two patients presented with subarachnoid hemorrhage, one with cognitive impairment, one with dizziness, and one with intermittent headache. DSA demonstrated that three cases were complicated by intracranial aneurysms, one by dural arteriovenous fistula, and one by rete aneurysm. Three patients underwent endovascular treatment and one underwent bypass surgery. No patient died or experienced cerebrovascular accident during short-term follow-up.ConclusionsICA agenesis can be complicated by disorders such as intracranial aneurysm, rete aneurysm, and dural arteriovenous fistula. This suggests that ICA agenesis is associated with a tendency towards disrupted cerebrovascular homeostasis resulting from altered hemodynamics. |
| first_indexed | 2024-04-12T08:38:10Z |
| format | Article |
| id | doaj.art-167ffbad87f44feca6c6988c2d0e6259 |
| institution | Directory Open Access Journal |
| issn | 2296-875X |
| language | English |
| last_indexed | 2024-04-12T08:38:10Z |
| publishDate | 2022-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Surgery |
| spelling | doaj.art-167ffbad87f44feca6c6988c2d0e62592022-12-22T03:39:57ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2022-11-01910.3389/fsurg.2022.953697953697Cerebrovascular disorders associated with agenesis of the internal carotid artery: Findings on digital subtraction angiographyXiaolong XuHongjian ShenHongyu MaXiaoxi ZhangLei ZhangQiang LiRui ZhaoDongwei DaiZifu LiPengfei YangJianmin LiuObjectiveAgenesis of the internal carotid artery (ICA) is a rare vascular condition that is complicated by intracranial aneurysms and rete mirabile. The altered hemodynamics caused by this distinctive cerebrovascular angioarchitecture can cause ischemic or hemorrhagic accidents. Data on clinical and radiographic features have been limited to describing this vascular pattern. We present five cases of agenesis of the internal carotid artery confirmed by digital subtraction angiography (DSA) and further investigate the influence of altered angioarchitecture on the integrity of intracranial morphology.MethodsCases of ICA anomalies were screened from the patients who underwent DSA in two hospitals. Clinical manifestation, radiographic features, management, and outcomes were retrospectively reviewed.ResultsFive patients [mean age 44 years (range, 30–65 years)] were included. Two patients presented with subarachnoid hemorrhage, one with cognitive impairment, one with dizziness, and one with intermittent headache. DSA demonstrated that three cases were complicated by intracranial aneurysms, one by dural arteriovenous fistula, and one by rete aneurysm. Three patients underwent endovascular treatment and one underwent bypass surgery. No patient died or experienced cerebrovascular accident during short-term follow-up.ConclusionsICA agenesis can be complicated by disorders such as intracranial aneurysm, rete aneurysm, and dural arteriovenous fistula. This suggests that ICA agenesis is associated with a tendency towards disrupted cerebrovascular homeostasis resulting from altered hemodynamics.https://www.frontiersin.org/articles/10.3389/fsurg.2022.953697/fullinternal carotid arteryagenesisaneurysmrete mirabiledural arteriovenous fistula |
| spellingShingle | Xiaolong Xu Hongjian Shen Hongyu Ma Xiaoxi Zhang Lei Zhang Qiang Li Rui Zhao Dongwei Dai Zifu Li Pengfei Yang Jianmin Liu Cerebrovascular disorders associated with agenesis of the internal carotid artery: Findings on digital subtraction angiography Frontiers in Surgery internal carotid artery agenesis aneurysm rete mirabile dural arteriovenous fistula |
| title | Cerebrovascular disorders associated with agenesis of the internal carotid artery: Findings on digital subtraction angiography |
| title_full | Cerebrovascular disorders associated with agenesis of the internal carotid artery: Findings on digital subtraction angiography |
| title_fullStr | Cerebrovascular disorders associated with agenesis of the internal carotid artery: Findings on digital subtraction angiography |
| title_full_unstemmed | Cerebrovascular disorders associated with agenesis of the internal carotid artery: Findings on digital subtraction angiography |
| title_short | Cerebrovascular disorders associated with agenesis of the internal carotid artery: Findings on digital subtraction angiography |
| title_sort | cerebrovascular disorders associated with agenesis of the internal carotid artery findings on digital subtraction angiography |
| topic | internal carotid artery agenesis aneurysm rete mirabile dural arteriovenous fistula |
| url | https://www.frontiersin.org/articles/10.3389/fsurg.2022.953697/full |
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