Kv4 channels underlie the subthreshold-operating A-type K<sup>+</sup>-current in nociceptive dorsal root ganglion neurons

Kv4 channels underlie the subthreshold-operating A-type K<sup>+</sup>-current in nociceptive dorsal root ganglion neurons

The dorsal root ganglion (DRG) contains heterogeneous populations of sensory neurons including primary nociceptive neurons and C-fibers implicated in pain signaling.&nbsp; Recent studies have demonstrated DRG hyperexcitability associated with downregulation of A-type K<sup>+</sup> ch...

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Bibliographic Details
Main Authors: Thanawath R Na Phuket, Manuel L Covarrubias
Format: Article
Language:English
Published: Frontiers Media S.A. 2009-07-01
Series:Frontiers in Molecular Neuroscience
Subjects:
RT-PCR
dominant-negative suppression
nociceptive neurons
nucleofection
voltage-gated K+ channels
Online Access:http://journal.frontiersin.org/Journal/10.3389/neuro.02.003.2009/full

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