m6A Reader: Epitranscriptome Target Prediction and Functional Characterization of N6-Methyladenosine (m6A) Readers

m6A Reader: Epitranscriptome Target Prediction and Functional Characterization of N6-Methyladenosine (m6A) Readers

N6-methyladenosine (m6A) is the most abundant post-transcriptional modification in mRNA, and regulates critical biological functions via m6A reader proteins that bind to m6A-containing transcripts. There exist multiple m6A reader proteins in the human genome, but their respective binding specificity...

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Bibliographic Details
Main Authors: Di Zhen, Yuxuan Wu, Yuxin Zhang, Kunqi Chen, Bowen Song, Haiqi Xu, Yujiao Tang, Zhen Wei, Jia Meng
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
N6-methyladenosine
m6A reader
machine learning (ML)
YTH domain
eIF3a
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00741/full

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