Mesenchymal stem cell-derived exosomes enriched with miR-218 reduce the epithelial–mesenchymal transition and angiogenesis in triple-negative breast cancer cells

Mesenchymal stem cell-derived exosomes enriched with miR-218 reduce the epithelial–mesenchymal transition and angiogenesis in triple-negative breast cancer cells

Abstract Background The epithelial–mesenchymal transition (EMT) and angiogenesis are morphogenetic processes implicated in tumor invasion and metastasis. It is found that the aberrant expression of microRNAs (miRNAs) contributes to these processes. Exosomes are considered potential natural vehicles...

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Bibliographic Details
Main Authors: Samaneh Shojaei, Maryam Moradi-Chaleshtori, Mahdi Paryan, Ameneh Koochaki, Kazem Sharifi, Samira Mohammadi-Yeganeh
Format: Article
Language:English
Published: BMC 2023-11-01
Series:European Journal of Medical Research
Subjects:
Triple-negative breast cancer
Mesenchymal stem cells
Exosomes
miR-218
EMT
Angiogenesis
Online Access:https://doi.org/10.1186/s40001-023-01463-2

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