GDF15 Supports the Inflammatory Response of PdL Fibroblasts Stimulated by <i>P. gingivalis</i> LPS and Concurrent Compression
Periodontitis is characterized by bacterially induced inflammatory destruction of periodontal tissue. This also affects fibroblasts of the human periodontal ligaments (HPdLF), which play a coordinating role in force-induced tissue and alveolar bone remodeling. Excessive inflammation in the oral tiss...
Main Authors: | Albert Stemmler, Judit Symmank, Julia Steinmetz, Katrin von Brandenstein, Christoph-Ludwig Hennig, Collin Jacobs |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-12-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/22/24/13608 |
Similar Items
-
GDF15 Contributes to the Regulation of the Mechanosensitive Responses of PdL Fibroblasts through the Modulation of IL-37
by: Julia Steinmetz, et al.
Published: (2024-02-01) -
GDF15 Modulates the Zoledronic-Acid-Induced Hyperinflammatory Mechanoresponse of Periodontal Ligament Fibroblasts
by: Ann Nitzsche, et al.
Published: (2024-01-01) -
GDF15 Promotes the Osteogenic Cell Fate of Periodontal Ligament Fibroblasts, thus Affecting Their Mechanobiological Response
by: Lukas Lösch, et al.
Published: (2023-06-01) -
Hyperlipidemic Conditions Impact Force-Induced Inflammatory Response of Human Periodontal Ligament Fibroblasts Concomitantly Challenged with <i>P. gingivalis</i>-LPS
by: Judit Symmank, et al.
Published: (2021-06-01) -
Supraphysiologic Administration of GDF11 Induces Cachexia in Part by Upregulating GDF15
by: Juli E. Jones, et al.
Published: (2018-02-01)