The loopy world of cohesin

DNA loops can be formed by a mechanism in which the cohesin complex pulls DNA strands through its ring structure using biased Brownian motion.

Bibliographic Details
Main Authors: Kazuhiro Maeshima, Shiori Iida
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-07-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/71585
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author Kazuhiro Maeshima
Shiori Iida
author_facet Kazuhiro Maeshima
Shiori Iida
author_sort Kazuhiro Maeshima
collection DOAJ
description DNA loops can be formed by a mechanism in which the cohesin complex pulls DNA strands through its ring structure using biased Brownian motion.
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institution Directory Open Access Journal
issn 2050-084X
language English
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spelling doaj.art-1689dcca599045b689484a986c1b8cef2022-12-22T03:52:55ZengeLife Sciences Publications LtdeLife2050-084X2021-07-011010.7554/eLife.71585The loopy world of cohesinKazuhiro Maeshima0https://orcid.org/0000-0003-3909-0341Shiori Iida1https://orcid.org/0000-0002-1115-4705Genome Dynamics Laboratory, National Institute of Genetics, Mishima, Japan; Department of Genetics, School of Life Sciences, Sokendai (Graduate University for Advanced Studies), Mishima, JapanGenome Dynamics Laboratory, National Institute of Genetics, Mishima, Japan; Department of Genetics, School of Life Sciences, Sokendai (Graduate University for Advanced Studies), Mishima, JapanDNA loops can be formed by a mechanism in which the cohesin complex pulls DNA strands through its ring structure using biased Brownian motion.https://elifesciences.org/articles/71585cohesinsmc complexessister chromatid cohesionDNA loop extrusionstructural biologybiophysical simulation
spellingShingle Kazuhiro Maeshima
Shiori Iida
The loopy world of cohesin
eLife
cohesin
smc complexes
sister chromatid cohesion
DNA loop extrusion
structural biology
biophysical simulation
title The loopy world of cohesin
title_full The loopy world of cohesin
title_fullStr The loopy world of cohesin
title_full_unstemmed The loopy world of cohesin
title_short The loopy world of cohesin
title_sort loopy world of cohesin
topic cohesin
smc complexes
sister chromatid cohesion
DNA loop extrusion
structural biology
biophysical simulation
url https://elifesciences.org/articles/71585
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