EARLY DIFFERENTIAL DIAGNOSTICS AND PROLONGED IMMUNOMODULATORY THERAPY OF CHRONIC INFLAMMATORY DEMYELINATING DISEASES OF CENTRAL NERVOUS SYSTEM IN CHILDREN AND ADOLESCENTS
Inflammatory demyelinating diseases in children and adolescents are sufficient problem of modern medicine. Its topicality is conditioned by as traditionally high prevalence of acute demyelinating conditions (acute disseminated encephalomyelitis) as increase of morbidity with chronic demyelinating fo...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
"Paediatrician" Publishers LLC
2009-11-01
|
| Series: | Вопросы современной педиатрии |
| Online Access: | https://vsp.spr-journal.ru/jour/article/view/1210 |
| _version_ | 1826561903332163584 |
|---|---|
| author | O.V. Bykova A.N. Platonova N.V. Gol'tsova G.V. Kuznetsova L.M. Kuzenkova A.N. Boiko |
| author_facet | O.V. Bykova A.N. Platonova N.V. Gol'tsova G.V. Kuznetsova L.M. Kuzenkova A.N. Boiko |
| author_sort | O.V. Bykova |
| collection | DOAJ |
| description | Inflammatory demyelinating diseases in children and adolescents are sufficient problem of modern medicine. Its topicality is conditioned by as traditionally high prevalence of acute demyelinating conditions (acute disseminated encephalomyelitis) as increase of morbidity with chronic demyelinating forms of pathology (disseminated sclerosis) in children. The absence of clear diagnostic algorithm presents difficulties for the determination of tactics of treatment and prognosis on early stages of their development, e.g. at the time of maximal effectiveness of immunomodulatory medications. Besides, the list of medications for the prolonged immunomodulatory treatment of demyelinating diseases, registered in Russia, includes such drugs as interferon beta 1a for the subcutaneous injection, officially annotated for the use from 12-year old age.Key words: children, inflammatory demyelinating diseases, diagnostics, treatment.(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(6):139-145) |
| first_indexed | 2024-03-12T04:53:29Z |
| format | Article |
| id | doaj.art-168ccc6087884bd988cbdb36574a708a |
| institution | Directory Open Access Journal |
| issn | 1682-5527 1682-5535 |
| language | English |
| last_indexed | 2025-03-14T09:39:34Z |
| publishDate | 2009-11-01 |
| publisher | "Paediatrician" Publishers LLC |
| record_format | Article |
| series | Вопросы современной педиатрии |
| spelling | doaj.art-168ccc6087884bd988cbdb36574a708a2025-03-02T11:34:14Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352009-11-01861391451211EARLY DIFFERENTIAL DIAGNOSTICS AND PROLONGED IMMUNOMODULATORY THERAPY OF CHRONIC INFLAMMATORY DEMYELINATING DISEASES OF CENTRAL NERVOUS SYSTEM IN CHILDREN AND ADOLESCENTSO.V. Bykova0A.N. Platonova1N.V. Gol'tsova2G.V. Kuznetsova3L.M. Kuzenkova4A.N. Boiko5Scientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowRussian State Medical University, MoscowInflammatory demyelinating diseases in children and adolescents are sufficient problem of modern medicine. Its topicality is conditioned by as traditionally high prevalence of acute demyelinating conditions (acute disseminated encephalomyelitis) as increase of morbidity with chronic demyelinating forms of pathology (disseminated sclerosis) in children. The absence of clear diagnostic algorithm presents difficulties for the determination of tactics of treatment and prognosis on early stages of their development, e.g. at the time of maximal effectiveness of immunomodulatory medications. Besides, the list of medications for the prolonged immunomodulatory treatment of demyelinating diseases, registered in Russia, includes such drugs as interferon beta 1a for the subcutaneous injection, officially annotated for the use from 12-year old age.Key words: children, inflammatory demyelinating diseases, diagnostics, treatment.(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(6):139-145)https://vsp.spr-journal.ru/jour/article/view/1210 |
| spellingShingle | O.V. Bykova A.N. Platonova N.V. Gol'tsova G.V. Kuznetsova L.M. Kuzenkova A.N. Boiko EARLY DIFFERENTIAL DIAGNOSTICS AND PROLONGED IMMUNOMODULATORY THERAPY OF CHRONIC INFLAMMATORY DEMYELINATING DISEASES OF CENTRAL NERVOUS SYSTEM IN CHILDREN AND ADOLESCENTS Вопросы современной педиатрии |
| title | EARLY DIFFERENTIAL DIAGNOSTICS AND PROLONGED IMMUNOMODULATORY THERAPY OF CHRONIC INFLAMMATORY DEMYELINATING DISEASES OF CENTRAL NERVOUS SYSTEM IN CHILDREN AND ADOLESCENTS |
| title_full | EARLY DIFFERENTIAL DIAGNOSTICS AND PROLONGED IMMUNOMODULATORY THERAPY OF CHRONIC INFLAMMATORY DEMYELINATING DISEASES OF CENTRAL NERVOUS SYSTEM IN CHILDREN AND ADOLESCENTS |
| title_fullStr | EARLY DIFFERENTIAL DIAGNOSTICS AND PROLONGED IMMUNOMODULATORY THERAPY OF CHRONIC INFLAMMATORY DEMYELINATING DISEASES OF CENTRAL NERVOUS SYSTEM IN CHILDREN AND ADOLESCENTS |
| title_full_unstemmed | EARLY DIFFERENTIAL DIAGNOSTICS AND PROLONGED IMMUNOMODULATORY THERAPY OF CHRONIC INFLAMMATORY DEMYELINATING DISEASES OF CENTRAL NERVOUS SYSTEM IN CHILDREN AND ADOLESCENTS |
| title_short | EARLY DIFFERENTIAL DIAGNOSTICS AND PROLONGED IMMUNOMODULATORY THERAPY OF CHRONIC INFLAMMATORY DEMYELINATING DISEASES OF CENTRAL NERVOUS SYSTEM IN CHILDREN AND ADOLESCENTS |
| title_sort | early differential diagnostics and prolonged immunomodulatory therapy of chronic inflammatory demyelinating diseases of central nervous system in children and adolescents |
| url | https://vsp.spr-journal.ru/jour/article/view/1210 |
| work_keys_str_mv | AT ovbykova earlydifferentialdiagnosticsandprolongedimmunomodulatorytherapyofchronicinflammatorydemyelinatingdiseasesofcentralnervoussysteminchildrenandadolescents AT anplatonova earlydifferentialdiagnosticsandprolongedimmunomodulatorytherapyofchronicinflammatorydemyelinatingdiseasesofcentralnervoussysteminchildrenandadolescents AT nvgoltsova earlydifferentialdiagnosticsandprolongedimmunomodulatorytherapyofchronicinflammatorydemyelinatingdiseasesofcentralnervoussysteminchildrenandadolescents AT gvkuznetsova earlydifferentialdiagnosticsandprolongedimmunomodulatorytherapyofchronicinflammatorydemyelinatingdiseasesofcentralnervoussysteminchildrenandadolescents AT lmkuzenkova earlydifferentialdiagnosticsandprolongedimmunomodulatorytherapyofchronicinflammatorydemyelinatingdiseasesofcentralnervoussysteminchildrenandadolescents AT anboiko earlydifferentialdiagnosticsandprolongedimmunomodulatorytherapyofchronicinflammatorydemyelinatingdiseasesofcentralnervoussysteminchildrenandadolescents |