Lens epithelium cell ferroptosis mediated by m6A-lncRNA and GPX4 expression in lens tissue of age-related cataract

Lens epithelium cell ferroptosis mediated by m6A-lncRNA and GPX4 expression in lens tissue of age-related cataract

Abstract Background In the present study, we explored the role of N6-methyladenosine (m6A) modification of long non-coding RNAs (lncRNAs) and its association with ferroptosis in lens epithelium cells (LECs) of age-related cataract (ARC). Methods Through m6A RNA immunoprecipitation sequencing (m6A-RI...

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Bibliographic Details
Main Authors: Yong Wang, Pengfei Li, Congyu Wang, Sijie Bao, Siwen Wang, Guowei Zhang, Xi Zou, Jian Wu, Yu Guan, Min Ji, Huaijin Guan
Format: Article
Language:English
Published: BMC 2023-12-01
Series:BMC Ophthalmology
Subjects:
Age-related cataract
N6-methyladenosine
Long noncoding RNA
Ferroptosis
Online Access:https://doi.org/10.1186/s12886-023-03205-8

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