The basic chemistry of exercise-induced DNA oxidation: oxidative damage, redox signalling and their interplay

Acute exercise increases reactive oxygen and nitrogen species generation. This phenomenon is associated with two major outcomes: (1) redox signalling and (2) macromolecule damage. Mechanistic knowledge of how exercise-induced redox signalling and macromolecule damage are interlinked is limited. This...

Full description

Bibliographic Details
Main Authors: James Nathan Cobley, Nikos V Margaritelis, James P Morton, Graeme Leonard Close, Michalis G. Nikolaidis, John K Malone
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-06-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2015.00182/full