Phospholipids of APOE lipoproteins activate microglia in an isoform-specific manner in preclinical models of Alzheimer’s disease
Microglia can clear amyloid plaques in Alzheimer’s disease. Here, the authors show that specific isoforms of the phospholipid forming APOE lipoproteins activate microglia in pre-clinical mouse models of Alzheimer’s disease.
| Main Authors: | , , , , , , , , , , , , |
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| פורמט: | Article |
| שפה: | English |
| יצא לאור: |
Nature Portfolio
2021-06-01
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| סדרה: | Nature Communications |
| גישה מקוונת: | https://doi.org/10.1038/s41467-021-23762-0 |