Occupational Risk Factors for SARS-CoV-2 Infection in Hospital Health Care Workers: A Prospective Nested Case-Control Study
<b>Introduction</b>: Health Care Workers (HCWs) are at a particular high risk of SARS-CoV-2 infection due to direct and indirect exposure to COVID-19 patients and Aerosol-Generating Procedures (AGPs). The aim of the study was to assess the risk factors for SARS-CoV-2 infection in HCWs ex...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-02-01
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| Series: | Life |
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| Online Access: | https://www.mdpi.com/2075-1729/12/2/263 |
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| author | Alex Dusefante Corrado Negro Pierlanfranco D’Agaro Ludovica Segat Antonio Purpuri Luca Cegolon Francesca Larese Filon |
| author_facet | Alex Dusefante Corrado Negro Pierlanfranco D’Agaro Ludovica Segat Antonio Purpuri Luca Cegolon Francesca Larese Filon |
| author_sort | Alex Dusefante |
| collection | DOAJ |
| description | <b>Introduction</b>: Health Care Workers (HCWs) are at a particular high risk of SARS-CoV-2 infection due to direct and indirect exposure to COVID-19 patients and Aerosol-Generating Procedures (AGPs). The aim of the study was to assess the risk factors for SARS-CoV-2 infection in HCWs exposed to COVID-19 patients, to evaluate the adherence and effectiveness of Infection Prevention and Control (IPC) measures, to describe the clinical presentation for SARS-CoV-2 infection in HCWs and to determine serological responses in HCWs. <b>Methods</b>: HCWs exposed to COVID-19 patients during the previous 14 days with a confirmed case status were recruited as cases; HCWs exposed to COVID-19 patients during the previous 14 days in the same ward without a suspected/probable/confirmed case status were recruited as controls. Serum samples were collected as soon as possible and after 21–28 days from all participants. Data were collected with a WHO standardized questionnaire as soon as possible and after 21–28 days. <b>Results</b>: All social, occupational and personal variables considered were not associated with an increased risk of SARS-CoV-2 infection. <b>Conclusions</b>: Our study showed a high knowledge of IPC measures and very high PPE use among HCWs. |
| first_indexed | 2024-03-09T21:34:02Z |
| format | Article |
| id | doaj.art-169127996bbb49f181ad87ab713b70a8 |
| institution | Directory Open Access Journal |
| issn | 2075-1729 |
| language | English |
| last_indexed | 2024-03-09T21:34:02Z |
| publishDate | 2022-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Life |
| spelling | doaj.art-169127996bbb49f181ad87ab713b70a82023-11-23T20:46:38ZengMDPI AGLife2075-17292022-02-0112226310.3390/life12020263Occupational Risk Factors for SARS-CoV-2 Infection in Hospital Health Care Workers: A Prospective Nested Case-Control StudyAlex Dusefante0Corrado Negro1Pierlanfranco D’Agaro2Ludovica Segat3Antonio Purpuri4Luca Cegolon5Francesca Larese Filon6Clinical Unit of Occupational Medicine, Department of Medical, Surgical & Health Sciences, University of Trieste, 34129 Trieste, ItalyClinical Unit of Occupational Medicine, Department of Medical, Surgical & Health Sciences, University of Trieste, 34129 Trieste, ItalyHygiene & Public Health Clinical Unit, Department of Medical, Surgical & Health Sciences, University of Trieste, 34129 Trieste, ItalyHygiene & Public Health Clinical Unit, Department of Laboratory, University Health Agency Giuliano-Isontina (ASUGI), 34129 Trieste, ItalyClinical Unit of Occupational Medicine, Department of Medical, Surgical & Health Sciences, University of Trieste, 34129 Trieste, ItalyClinical Unit of Occupational Medicine, Department of Medical, Surgical & Health Sciences, University of Trieste, 34129 Trieste, ItalyClinical Unit of Occupational Medicine, Department of Medical, Surgical & Health Sciences, University of Trieste, 34129 Trieste, Italy<b>Introduction</b>: Health Care Workers (HCWs) are at a particular high risk of SARS-CoV-2 infection due to direct and indirect exposure to COVID-19 patients and Aerosol-Generating Procedures (AGPs). The aim of the study was to assess the risk factors for SARS-CoV-2 infection in HCWs exposed to COVID-19 patients, to evaluate the adherence and effectiveness of Infection Prevention and Control (IPC) measures, to describe the clinical presentation for SARS-CoV-2 infection in HCWs and to determine serological responses in HCWs. <b>Methods</b>: HCWs exposed to COVID-19 patients during the previous 14 days with a confirmed case status were recruited as cases; HCWs exposed to COVID-19 patients during the previous 14 days in the same ward without a suspected/probable/confirmed case status were recruited as controls. Serum samples were collected as soon as possible and after 21–28 days from all participants. Data were collected with a WHO standardized questionnaire as soon as possible and after 21–28 days. <b>Results</b>: All social, occupational and personal variables considered were not associated with an increased risk of SARS-CoV-2 infection. <b>Conclusions</b>: Our study showed a high knowledge of IPC measures and very high PPE use among HCWs.https://www.mdpi.com/2075-1729/12/2/263SARS-CoV-2COVID-19occupationalrisk factors |
| spellingShingle | Alex Dusefante Corrado Negro Pierlanfranco D’Agaro Ludovica Segat Antonio Purpuri Luca Cegolon Francesca Larese Filon Occupational Risk Factors for SARS-CoV-2 Infection in Hospital Health Care Workers: A Prospective Nested Case-Control Study Life SARS-CoV-2 COVID-19 occupational risk factors |
| title | Occupational Risk Factors for SARS-CoV-2 Infection in Hospital Health Care Workers: A Prospective Nested Case-Control Study |
| title_full | Occupational Risk Factors for SARS-CoV-2 Infection in Hospital Health Care Workers: A Prospective Nested Case-Control Study |
| title_fullStr | Occupational Risk Factors for SARS-CoV-2 Infection in Hospital Health Care Workers: A Prospective Nested Case-Control Study |
| title_full_unstemmed | Occupational Risk Factors for SARS-CoV-2 Infection in Hospital Health Care Workers: A Prospective Nested Case-Control Study |
| title_short | Occupational Risk Factors for SARS-CoV-2 Infection in Hospital Health Care Workers: A Prospective Nested Case-Control Study |
| title_sort | occupational risk factors for sars cov 2 infection in hospital health care workers a prospective nested case control study |
| topic | SARS-CoV-2 COVID-19 occupational risk factors |
| url | https://www.mdpi.com/2075-1729/12/2/263 |
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