Acute massive myelofibrosis with acutelymphoblastic leukemia

Acute myelofibrosis is characterized by pancytopenia of sudden onset, megakaryocytic hyperplasia, extensive bone marrow fibrosis, and the absence of organomegaly. Acute myelofibrosis in patients with acute lymphoblastic leukemia is extremely rare. We report a 4-year-old boy who was diagnosed as havi...

Full description

Bibliographic Details
Main Authors: Namık Özbek, Bülent Celasun, Feride Iffet Şahin, Meltem Gülşan, Barış Malbora, Zekai Avcı
Format: Article
Language:English
Published: Galenos Publishing House 2009-12-01
Series:Turkish Journal of Hematology
Subjects:
Online Access:http://www.journalagent.com/z4/download_fulltext.asp?pdir=tjh&plng=eng&un=TJH-18199
_version_ 1828027029370437632
author Namık Özbek
Bülent Celasun
Feride Iffet Şahin
Meltem Gülşan
Barış Malbora
Zekai Avcı
author_facet Namık Özbek
Bülent Celasun
Feride Iffet Şahin
Meltem Gülşan
Barış Malbora
Zekai Avcı
author_sort Namık Özbek
collection DOAJ
description Acute myelofibrosis is characterized by pancytopenia of sudden onset, megakaryocytic hyperplasia, extensive bone marrow fibrosis, and the absence of organomegaly. Acute myelofibrosis in patients with acute lymphoblastic leukemia is extremely rare. We report a 4-year-old boy who was diagnosed as having acute massive myelofibrosis and acute lymphoblastic leukemia. Performing bone marrow aspiration in this patient was difficult (a “dry tap”), and the diagnosis was established by means of a bone marrow biopsy and immunohistopathologic analysis. The prognostic significance of acute myelofibrosis in patients with acute lymphoblastic leukemia is not clear.
first_indexed 2024-04-10T13:28:43Z
format Article
id doaj.art-1693cb52410f490abfc5a857af7e71b4
institution Directory Open Access Journal
issn 1300-7777
1308-5263
language English
last_indexed 2024-04-10T13:28:43Z
publishDate 2009-12-01
publisher Galenos Publishing House
record_format Article
series Turkish Journal of Hematology
spelling doaj.art-1693cb52410f490abfc5a857af7e71b42023-02-15T16:11:45ZengGalenos Publishing HouseTurkish Journal of Hematology1300-77771308-52632009-12-012604204206Acute massive myelofibrosis with acutelymphoblastic leukemiaNamık ÖzbekBülent CelasunFeride Iffet ŞahinMeltem GülşanBarış MalboraZekai AvcıAcute myelofibrosis is characterized by pancytopenia of sudden onset, megakaryocytic hyperplasia, extensive bone marrow fibrosis, and the absence of organomegaly. Acute myelofibrosis in patients with acute lymphoblastic leukemia is extremely rare. We report a 4-year-old boy who was diagnosed as having acute massive myelofibrosis and acute lymphoblastic leukemia. Performing bone marrow aspiration in this patient was difficult (a “dry tap”), and the diagnosis was established by means of a bone marrow biopsy and immunohistopathologic analysis. The prognostic significance of acute myelofibrosis in patients with acute lymphoblastic leukemia is not clear.http://www.journalagent.com/z4/download_fulltext.asp?pdir=tjh&plng=eng&un=TJH-18199Acute myelofibrosisacute lymphoblastic leukemiadry tap
spellingShingle Namık Özbek
Bülent Celasun
Feride Iffet Şahin
Meltem Gülşan
Barış Malbora
Zekai Avcı
Acute massive myelofibrosis with acutelymphoblastic leukemia
Turkish Journal of Hematology
Acute myelofibrosis
acute lymphoblastic leukemia
dry tap
title Acute massive myelofibrosis with acutelymphoblastic leukemia
title_full Acute massive myelofibrosis with acutelymphoblastic leukemia
title_fullStr Acute massive myelofibrosis with acutelymphoblastic leukemia
title_full_unstemmed Acute massive myelofibrosis with acutelymphoblastic leukemia
title_short Acute massive myelofibrosis with acutelymphoblastic leukemia
title_sort acute massive myelofibrosis with acutelymphoblastic leukemia
topic Acute myelofibrosis
acute lymphoblastic leukemia
dry tap
url http://www.journalagent.com/z4/download_fulltext.asp?pdir=tjh&plng=eng&un=TJH-18199
work_keys_str_mv AT namıkozbek acutemassivemyelofibrosiswithacutelymphoblasticleukemia
AT bulentcelasun acutemassivemyelofibrosiswithacutelymphoblasticleukemia
AT ferideiffetsahin acutemassivemyelofibrosiswithacutelymphoblasticleukemia
AT meltemgulsan acutemassivemyelofibrosiswithacutelymphoblasticleukemia
AT barısmalbora acutemassivemyelofibrosiswithacutelymphoblasticleukemia
AT zekaiavcı acutemassivemyelofibrosiswithacutelymphoblasticleukemia