Circulating exosome-like vesicles of humans with nondiabetic obesity impaired islet β-cell proliferation, which was associated with decreased Omentin-1 protein cargo

The regulation of β-cell mass in the status of nondiabetic obesity remains not well understood. We aimed to investigate the role of circulating exosome-like vesicles (ELVs) isolated from humans with simple obesity in the regulation of islet β-cell mass. Between June 2017 and July 2019, 81 subjects w...

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Bibliographic Details
Main Authors: Qian Ge, Xinxin Xie, Xiangjun Chen, Rongfeng Huang, Cheng-Xue Rui, Qianna Zhen, Renzhi Hu, Min Wu, Xiaoqiu Xiao, Xi Li
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-07-01
Series:Genes and Diseases
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304220301689