High-dimensional topographic organization of visual features in the primate temporal lobe
Abstract The inferotemporal cortex supports our supreme object recognition ability. Numerous studies have been conducted to elucidate the functional organization of this brain area, but there are still important questions that remain unanswered, including how this organization differs between humans...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2023-09-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-023-41584-0 |
| _version_ | 1797558356867547136 |
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| author | Mengna Yao Bincheng Wen Mingpo Yang Jiebin Guo Haozhou Jiang Chao Feng Yilei Cao Huiguang He Le Chang |
| author_facet | Mengna Yao Bincheng Wen Mingpo Yang Jiebin Guo Haozhou Jiang Chao Feng Yilei Cao Huiguang He Le Chang |
| author_sort | Mengna Yao |
| collection | DOAJ |
| description | Abstract The inferotemporal cortex supports our supreme object recognition ability. Numerous studies have been conducted to elucidate the functional organization of this brain area, but there are still important questions that remain unanswered, including how this organization differs between humans and non-human primates. Here, we use deep neural networks trained on object categorization to construct a 25-dimensional space of visual features, and systematically measure the spatial organization of feature preference in both male monkey brains and human brains using fMRI. These feature maps allow us to predict the selectivity of a previously unknown region in monkey brains, which is corroborated by additional fMRI and electrophysiology experiments. These maps also enable quantitative analyses of the topographic organization of the temporal lobe, demonstrating the existence of a pair of orthogonal gradients that differ in spatial scale and revealing significant differences in the functional organization of high-level visual areas between monkey and human brains. |
| first_indexed | 2024-03-10T17:29:04Z |
| format | Article |
| id | doaj.art-16945bf64aaa4ecf8af74e80ff8f8a49 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-03-10T17:29:04Z |
| publishDate | 2023-09-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-16945bf64aaa4ecf8af74e80ff8f8a492023-11-20T10:02:55ZengNature PortfolioNature Communications2041-17232023-09-0114112310.1038/s41467-023-41584-0High-dimensional topographic organization of visual features in the primate temporal lobeMengna Yao0Bincheng Wen1Mingpo Yang2Jiebin Guo3Haozhou Jiang4Chao Feng5Yilei Cao6Huiguang He7Le Chang8Institute of Neuroscience, Key Laboratory of Primate Neurobiology, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of SciencesInstitute of Neuroscience, Key Laboratory of Primate Neurobiology, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of SciencesInstitute of Neuroscience, Key Laboratory of Primate Neurobiology, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of SciencesInstitute of Neuroscience, Key Laboratory of Primate Neurobiology, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of SciencesInstitute of Neuroscience, Key Laboratory of Primate Neurobiology, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of SciencesInstitute of Neuroscience, Key Laboratory of Primate Neurobiology, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of SciencesInstitute of Neuroscience, Key Laboratory of Primate Neurobiology, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of SciencesUniversity of Chinese Academy of SciencesInstitute of Neuroscience, Key Laboratory of Primate Neurobiology, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of SciencesAbstract The inferotemporal cortex supports our supreme object recognition ability. Numerous studies have been conducted to elucidate the functional organization of this brain area, but there are still important questions that remain unanswered, including how this organization differs between humans and non-human primates. Here, we use deep neural networks trained on object categorization to construct a 25-dimensional space of visual features, and systematically measure the spatial organization of feature preference in both male monkey brains and human brains using fMRI. These feature maps allow us to predict the selectivity of a previously unknown region in monkey brains, which is corroborated by additional fMRI and electrophysiology experiments. These maps also enable quantitative analyses of the topographic organization of the temporal lobe, demonstrating the existence of a pair of orthogonal gradients that differ in spatial scale and revealing significant differences in the functional organization of high-level visual areas between monkey and human brains.https://doi.org/10.1038/s41467-023-41584-0 |
| spellingShingle | Mengna Yao Bincheng Wen Mingpo Yang Jiebin Guo Haozhou Jiang Chao Feng Yilei Cao Huiguang He Le Chang High-dimensional topographic organization of visual features in the primate temporal lobe Nature Communications |
| title | High-dimensional topographic organization of visual features in the primate temporal lobe |
| title_full | High-dimensional topographic organization of visual features in the primate temporal lobe |
| title_fullStr | High-dimensional topographic organization of visual features in the primate temporal lobe |
| title_full_unstemmed | High-dimensional topographic organization of visual features in the primate temporal lobe |
| title_short | High-dimensional topographic organization of visual features in the primate temporal lobe |
| title_sort | high dimensional topographic organization of visual features in the primate temporal lobe |
| url | https://doi.org/10.1038/s41467-023-41584-0 |
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