Expression of a recombinant hybrid antimicrobial peptide magainin II-cecropin B in the mycelium of the medicinal fungus Cordyceps militaris and its validation in mice

Expression of a recombinant hybrid antimicrobial peptide magainin II-cecropin B in the mycelium of the medicinal fungus Cordyceps militaris and its validation in mice

Abstract Background Antibiotic residues can cause antibiotic resistance in livestock and their food safety-related issues have increased the consumer demand for products lacking these residues. Hence, developing safe and effective antibiotic alternatives is important to the animal feed industry. Wit...

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Bibliographic Details
Main Authors: Min Zhang, Yuanlong Shan, Hongtao Gao, Bin Wang, Xin Liu, Yuanyuan Dong, Xiuming Liu, Na Yao, Yonggang Zhou, Xiaowei Li, Haiyan Li
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Microbial Cell Factories
Subjects:
Hybrid antimicrobial peptide
Cordyceps militaris
Recombinant expression
Escherichia coli (ATCC 25922)
Immunomodulatory
Feed additive
Online Access:http://link.springer.com/article/10.1186/s12934-018-0865-3

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