Quercetin 3-O-rutinoside prevents radiation induced oxidative damage and inflammation by coordinated regulation of Nrf2/ NF-κB/ NLRP3- inflammasome signaling in gastrointestine

Quercetin 3-O-rutinoside prevents radiation induced oxidative damage and inflammation by coordinated regulation of Nrf2/ NF-κB/ NLRP3- inflammasome signaling in gastrointestine

Background: Irradiation causes extensive alteration in the cellular homeostasis leading to severe organ damage and dysfunction. The lack of understanding of the mechanism conferring radioprotection is often considered a major limitation in the development of agents that suppress the damaging effects...

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Bibliographic Details
Main Authors: Suchitra Sharma, Akshu Dahiya, Subodh Kumar, Yogesh Kumar Verma, Ajaswrata Dutta
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Phytomedicine Plus
Subjects:
Quercetin-3-O-rutinoside
Intestine
Gamma radiation
Oxidative stress
Inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S2667031322001646

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