Quercetin 3-O-rutinoside prevents radiation induced oxidative damage and inflammation by coordinated regulation of Nrf2/ NF-κB/ NLRP3- inflammasome signaling in gastrointestine
Background: Irradiation causes extensive alteration in the cellular homeostasis leading to severe organ damage and dysfunction. The lack of understanding of the mechanism conferring radioprotection is often considered a major limitation in the development of agents that suppress the damaging effects...
Main Authors: | Suchitra Sharma, Akshu Dahiya, Subodh Kumar, Yogesh Kumar Verma, Ajaswrata Dutta |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-02-01
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Series: | Phytomedicine Plus |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2667031322001646 |
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