The Mitochondrial Protein MitoNEET as a Probe for the Allostery of Glutamate Dehydrogenase

The proteins glutamate dehydrogenase (GDH) and mitoNEET are both targets of drug development efforts to treat metabolic disorders, cancer, and neurodegenerative diseases. However, these two proteins differ starkly in the current knowledge about ligand binding sites. MitoNEET is a [2Fe-2S]-containing...

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Détails bibliographiques
Auteurs principaux: Chimere Nnatubeugo, Erica Johnson, Sarah Gisondi, Felicia Roland, Werner J. Geldenhuys, Michael A. Menze, Mary E. Konkle
Format: Article
Langue:English
Publié: MDPI AG 2022-11-01
Collection:Molecules
Sujets:
Accès en ligne:https://www.mdpi.com/1420-3049/27/23/8314