The role of small non-coding RNAs (sncRNAs) in male infertility: A scoping review
Objective: To give a brief overview of the field of epigenetics and the potential predictive power that small non-coding RNA (sncRNA) may hold in relation to improving the treatment and diagnosis of male infertility. Methods: PRISMA-ScR was used as the scoping review guideline for this investigation...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Asian Pacific Journal of Reproduction |
| Subjects: | |
| Online Access: | http://www.apjr.net/article.asp?issn=2305-0500;year=2023;volume=12;issue=5;spage=201;epage=210;aulast=Kaya |
| _version_ | 1797352208126181376 |
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| author | Hacer Kaya Cakir Onur Eroglu |
| author_facet | Hacer Kaya Cakir Onur Eroglu |
| author_sort | Hacer Kaya Cakir |
| collection | DOAJ |
| description | Objective: To give a brief overview of the field of epigenetics and the potential predictive power that small non-coding RNA (sncRNA) may hold in relation to improving the treatment and diagnosis of male infertility.
Methods: PRISMA-ScR was used as the scoping review guideline for this investigation. All article data here have been accessed from MEDLINE–PubMed, Science Direct, EBSCO, Scopus, Sage Journals, and Google Scholar. The terms "small non coding RNA, male, infertility, miRNA, sperm" were used in the search between 2015 and 2023.
Results: The study comprised 35 publications in total. Several sncRNAs, miR-155, miR-16, miR-196, miR-525-3p, miR-891 were found to be effective in regulating the mechanism of spermatozoa processing in the infertility of men. sncRNA can be used as a biomarker of male infertility.
Conclusions: sncRNAs can act as biomarkers for the diagnosis of reproductive diseases. Actually, by recognizing sncRNAs and their mechanisms, a new way to treat infertile men would be paved. The functional annotation of sncRNAs in spermatogenesis is still in its infancy but has enormous potential. This is despite the fact that many potential sncRNAs have been found to date with the use of cutting-edge technology and publicly accessible sncRNA annotation tools. |
| first_indexed | 2024-03-08T13:12:59Z |
| format | Article |
| id | doaj.art-1697943bec7b48348be8acfb45db7962 |
| institution | Directory Open Access Journal |
| issn | 2305-0500 2305-0519 |
| language | English |
| last_indexed | 2024-03-08T13:12:59Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Asian Pacific Journal of Reproduction |
| spelling | doaj.art-1697943bec7b48348be8acfb45db79622024-01-18T10:41:53ZengWolters Kluwer Medknow PublicationsAsian Pacific Journal of Reproduction2305-05002305-05192023-01-0112520121010.4103/2305-0500.386121The role of small non-coding RNAs (sncRNAs) in male infertility: A scoping reviewHacer Kaya CakirOnur ErogluObjective: To give a brief overview of the field of epigenetics and the potential predictive power that small non-coding RNA (sncRNA) may hold in relation to improving the treatment and diagnosis of male infertility. Methods: PRISMA-ScR was used as the scoping review guideline for this investigation. All article data here have been accessed from MEDLINE–PubMed, Science Direct, EBSCO, Scopus, Sage Journals, and Google Scholar. The terms "small non coding RNA, male, infertility, miRNA, sperm" were used in the search between 2015 and 2023. Results: The study comprised 35 publications in total. Several sncRNAs, miR-155, miR-16, miR-196, miR-525-3p, miR-891 were found to be effective in regulating the mechanism of spermatozoa processing in the infertility of men. sncRNA can be used as a biomarker of male infertility. Conclusions: sncRNAs can act as biomarkers for the diagnosis of reproductive diseases. Actually, by recognizing sncRNAs and their mechanisms, a new way to treat infertile men would be paved. The functional annotation of sncRNAs in spermatogenesis is still in its infancy but has enormous potential. This is despite the fact that many potential sncRNAs have been found to date with the use of cutting-edge technology and publicly accessible sncRNA annotation tools.http://www.apjr.net/article.asp?issn=2305-0500;year=2023;volume=12;issue=5;spage=201;epage=210;aulast=Kayamale infertility; mirna; small untranslated rna; sncrnas; sperm; next-generation sequencing; real-time pcr |
| spellingShingle | Hacer Kaya Cakir Onur Eroglu The role of small non-coding RNAs (sncRNAs) in male infertility: A scoping review Asian Pacific Journal of Reproduction male infertility; mirna; small untranslated rna; sncrnas; sperm; next-generation sequencing; real-time pcr |
| title | The role of small non-coding RNAs (sncRNAs) in male infertility: A scoping review |
| title_full | The role of small non-coding RNAs (sncRNAs) in male infertility: A scoping review |
| title_fullStr | The role of small non-coding RNAs (sncRNAs) in male infertility: A scoping review |
| title_full_unstemmed | The role of small non-coding RNAs (sncRNAs) in male infertility: A scoping review |
| title_short | The role of small non-coding RNAs (sncRNAs) in male infertility: A scoping review |
| title_sort | role of small non coding rnas sncrnas in male infertility a scoping review |
| topic | male infertility; mirna; small untranslated rna; sncrnas; sperm; next-generation sequencing; real-time pcr |
| url | http://www.apjr.net/article.asp?issn=2305-0500;year=2023;volume=12;issue=5;spage=201;epage=210;aulast=Kaya |
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