Epidemiological Factors and Pathomorphologic Characteristics of Hydatidiform Mole
<strong>Introduction:</strong> Hydatidiform mole is a gestational trophoblastic disease characterized by a range of disorders of abnormal trophoblastic proliferation.<br /><strong>Methods:</strong> This was a retrospective study of 70 singletone pregnancies until the 12...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
University of Sarajevo
2013-09-01
|
| Series: | Journal of Health Sciences |
| Subjects: | |
| Online Access: | http://jhsci.ba/OJS/index.php/jhsci/article/view/77 |
| Summary: | <strong>Introduction:</strong> Hydatidiform mole is a gestational trophoblastic disease characterized by a range of disorders of abnormal trophoblastic proliferation.<br /><strong>Methods:</strong> This was a retrospective study of 70 singletone pregnancies until the 12th week of gestational age diagnosed with hydatidiform mole or spontaneously aborted physiological pregnancy. The pregnant<br />women had almost similar demographic features and were divided into two groups. 35 pregnant women with a molar pregnancy were included in the study group; while 35 pregnant women with physiological<br />pregnancy spontaneously aborted were included in the control group. Analyzed parameters included a pregnant woman’s age, blood type, parity and previous pregnancies (course and outcomes).<br /><strong>Results:</strong> In the study group 11.43% of cases had hydatidiform mola during previous pregnancies as well as the advanced average gestational age of an ongoing pregnancy (9.63±1.83 in contrast to 8.25±2.03<br />in the control group). The pregnant women with the hydatidiform mole were reported to have statistically significantly greater number of irregular villous borders (71.43%); slightly enlarged villi (54.29%); moderated<br />presence of cisterns (65.71%) as well as mild avascularisation of villi (57.14%).<br /><strong>Conclusion:</strong> It was concluded that a previous molar pregnancy represents the highest risk for hydtidiforme mole and the pathomorphologic analysis of vilous changes can be a reliable parameter for establishing<br />proper diagnosis of partial hydatidiform mole. |
|---|---|
| ISSN: | 2232-7576 1986-8049 |