Epidemiological Factors and Pathomorphologic Characteristics of Hydatidiform Mole
<strong>Introduction:</strong> Hydatidiform mole is a gestational trophoblastic disease characterized by a range of disorders of abnormal trophoblastic proliferation.<br /><strong>Methods:</strong> This was a retrospective study of 70 singletone pregnancies until the 12...
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| Format: | Article |
| Language: | English |
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University of Sarajevo
2013-09-01
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| Series: | Journal of Health Sciences |
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| Online Access: | http://jhsci.ba/OJS/index.php/jhsci/article/view/77 |
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| author | Lejla Muminhodžić Gordana Bogdanović Dženita Ljuca Adnan Babović |
| author_facet | Lejla Muminhodžić Gordana Bogdanović Dženita Ljuca Adnan Babović |
| author_sort | Lejla Muminhodžić |
| collection | DOAJ |
| description | <strong>Introduction:</strong> Hydatidiform mole is a gestational trophoblastic disease characterized by a range of disorders of abnormal trophoblastic proliferation.<br /><strong>Methods:</strong> This was a retrospective study of 70 singletone pregnancies until the 12th week of gestational age diagnosed with hydatidiform mole or spontaneously aborted physiological pregnancy. The pregnant<br />women had almost similar demographic features and were divided into two groups. 35 pregnant women with a molar pregnancy were included in the study group; while 35 pregnant women with physiological<br />pregnancy spontaneously aborted were included in the control group. Analyzed parameters included a pregnant woman’s age, blood type, parity and previous pregnancies (course and outcomes).<br /><strong>Results:</strong> In the study group 11.43% of cases had hydatidiform mola during previous pregnancies as well as the advanced average gestational age of an ongoing pregnancy (9.63±1.83 in contrast to 8.25±2.03<br />in the control group). The pregnant women with the hydatidiform mole were reported to have statistically significantly greater number of irregular villous borders (71.43%); slightly enlarged villi (54.29%); moderated<br />presence of cisterns (65.71%) as well as mild avascularisation of villi (57.14%).<br /><strong>Conclusion:</strong> It was concluded that a previous molar pregnancy represents the highest risk for hydtidiforme mole and the pathomorphologic analysis of vilous changes can be a reliable parameter for establishing<br />proper diagnosis of partial hydatidiform mole. |
| first_indexed | 2024-12-12T19:04:43Z |
| format | Article |
| id | doaj.art-169a5206b338489196ff1ee03fca55ea |
| institution | Directory Open Access Journal |
| issn | 2232-7576 1986-8049 |
| language | English |
| last_indexed | 2024-12-12T19:04:43Z |
| publishDate | 2013-09-01 |
| publisher | University of Sarajevo |
| record_format | Article |
| series | Journal of Health Sciences |
| spelling | doaj.art-169a5206b338489196ff1ee03fca55ea2022-12-22T00:14:59ZengUniversity of SarajevoJournal of Health Sciences2232-75761986-80492013-09-0132129137Epidemiological Factors and Pathomorphologic Characteristics of Hydatidiform MoleLejla MuminhodžićGordana BogdanovićDženita LjucaAdnan Babović<strong>Introduction:</strong> Hydatidiform mole is a gestational trophoblastic disease characterized by a range of disorders of abnormal trophoblastic proliferation.<br /><strong>Methods:</strong> This was a retrospective study of 70 singletone pregnancies until the 12th week of gestational age diagnosed with hydatidiform mole or spontaneously aborted physiological pregnancy. The pregnant<br />women had almost similar demographic features and were divided into two groups. 35 pregnant women with a molar pregnancy were included in the study group; while 35 pregnant women with physiological<br />pregnancy spontaneously aborted were included in the control group. Analyzed parameters included a pregnant woman’s age, blood type, parity and previous pregnancies (course and outcomes).<br /><strong>Results:</strong> In the study group 11.43% of cases had hydatidiform mola during previous pregnancies as well as the advanced average gestational age of an ongoing pregnancy (9.63±1.83 in contrast to 8.25±2.03<br />in the control group). The pregnant women with the hydatidiform mole were reported to have statistically significantly greater number of irregular villous borders (71.43%); slightly enlarged villi (54.29%); moderated<br />presence of cisterns (65.71%) as well as mild avascularisation of villi (57.14%).<br /><strong>Conclusion:</strong> It was concluded that a previous molar pregnancy represents the highest risk for hydtidiforme mole and the pathomorphologic analysis of vilous changes can be a reliable parameter for establishing<br />proper diagnosis of partial hydatidiform mole.http://jhsci.ba/OJS/index.php/jhsci/article/view/77hydatidiform mole, epidemiologic factors, resorption villi |
| spellingShingle | Lejla Muminhodžić Gordana Bogdanović Dženita Ljuca Adnan Babović Epidemiological Factors and Pathomorphologic Characteristics of Hydatidiform Mole Journal of Health Sciences hydatidiform mole, epidemiologic factors, resorption villi |
| title | Epidemiological Factors and Pathomorphologic Characteristics of Hydatidiform Mole |
| title_full | Epidemiological Factors and Pathomorphologic Characteristics of Hydatidiform Mole |
| title_fullStr | Epidemiological Factors and Pathomorphologic Characteristics of Hydatidiform Mole |
| title_full_unstemmed | Epidemiological Factors and Pathomorphologic Characteristics of Hydatidiform Mole |
| title_short | Epidemiological Factors and Pathomorphologic Characteristics of Hydatidiform Mole |
| title_sort | epidemiological factors and pathomorphologic characteristics of hydatidiform mole |
| topic | hydatidiform mole, epidemiologic factors, resorption villi |
| url | http://jhsci.ba/OJS/index.php/jhsci/article/view/77 |
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