Stony coral tissue loss disease induces transcriptional signatures of in situ degradation of dysfunctional Symbiodiniaceae
Abstract Stony coral tissue loss disease (SCTLD), one of the most pervasive and virulent coral diseases on record, affects over 22 species of reef-building coral and is decimating reefs throughout the Caribbean. To understand how different coral species and their algal symbionts (family Symbiodiniac...
| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2023-05-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-023-38612-4 |
| _version_ | 1797817890097856512 |
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| author | Kelsey M. Beavers Emily W. Van Buren Ashley M. Rossin Madison A. Emery Alex J. Veglia Carly E. Karrick Nicholas J. MacKnight Bradford A. Dimos Sonora S. Meiling Tyler B. Smith Amy Apprill Erinn M. Muller Daniel M. Holstein Adrienne M. S. Correa Marilyn E. Brandt Laura D. Mydlarz |
| author_facet | Kelsey M. Beavers Emily W. Van Buren Ashley M. Rossin Madison A. Emery Alex J. Veglia Carly E. Karrick Nicholas J. MacKnight Bradford A. Dimos Sonora S. Meiling Tyler B. Smith Amy Apprill Erinn M. Muller Daniel M. Holstein Adrienne M. S. Correa Marilyn E. Brandt Laura D. Mydlarz |
| author_sort | Kelsey M. Beavers |
| collection | DOAJ |
| description | Abstract Stony coral tissue loss disease (SCTLD), one of the most pervasive and virulent coral diseases on record, affects over 22 species of reef-building coral and is decimating reefs throughout the Caribbean. To understand how different coral species and their algal symbionts (family Symbiodiniaceae) respond to this disease, we examine the gene expression profiles of colonies of five species of coral from a SCTLD transmission experiment. The included species vary in their purported susceptibilities to SCTLD, and we use this to inform gene expression analyses of both the coral animal and their Symbiodiniaceae. We identify orthologous coral genes exhibiting lineage-specific differences in expression that correlate to disease susceptibility, as well as genes that are differentially expressed in all coral species in response to SCTLD infection. We find that SCTLD infection induces increased expression of rab7, an established marker of in situ degradation of dysfunctional Symbiodiniaceae, in all coral species accompanied by genus-level shifts in Symbiodiniaceae photosystem and metabolism gene expression. Overall, our results indicate that SCTLD infection induces symbiophagy across coral species and that the severity of disease is influenced by Symbiodiniaceae identity. |
| first_indexed | 2024-03-13T09:00:09Z |
| format | Article |
| id | doaj.art-169ce08a61e34a13861116eda8b3715f |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-03-13T09:00:09Z |
| publishDate | 2023-05-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-169ce08a61e34a13861116eda8b3715f2023-05-28T11:21:14ZengNature PortfolioNature Communications2041-17232023-05-0114111510.1038/s41467-023-38612-4Stony coral tissue loss disease induces transcriptional signatures of in situ degradation of dysfunctional SymbiodiniaceaeKelsey M. Beavers0Emily W. Van Buren1Ashley M. Rossin2Madison A. Emery3Alex J. Veglia4Carly E. Karrick5Nicholas J. MacKnight6Bradford A. Dimos7Sonora S. Meiling8Tyler B. Smith9Amy Apprill10Erinn M. Muller11Daniel M. Holstein12Adrienne M. S. Correa13Marilyn E. Brandt14Laura D. Mydlarz15Biology Department, University of Texas at ArlingtonBiology Department, University of Texas at ArlingtonDepartment of Oceanography and Coastal Sciences, Louisiana State UniversityBiology Department, University of Texas at ArlingtonDepartment of BioSciences, Rice UniversityDepartment of BioSciences, Rice UniversityBiology Department, University of Texas at ArlingtonBiology Department, University of Texas at ArlingtonCenter for Marine and Environmental Studies, University of the Virgin IslandsCenter for Marine and Environmental Studies, University of the Virgin IslandsMarine Chemistry and Geochemistry Department, Woods Hole Oceanographic InstitutionMote Marine LaboratoryDepartment of Oceanography and Coastal Sciences, Louisiana State UniversityDepartment of BioSciences, Rice UniversityCenter for Marine and Environmental Studies, University of the Virgin IslandsBiology Department, University of Texas at ArlingtonAbstract Stony coral tissue loss disease (SCTLD), one of the most pervasive and virulent coral diseases on record, affects over 22 species of reef-building coral and is decimating reefs throughout the Caribbean. To understand how different coral species and their algal symbionts (family Symbiodiniaceae) respond to this disease, we examine the gene expression profiles of colonies of five species of coral from a SCTLD transmission experiment. The included species vary in their purported susceptibilities to SCTLD, and we use this to inform gene expression analyses of both the coral animal and their Symbiodiniaceae. We identify orthologous coral genes exhibiting lineage-specific differences in expression that correlate to disease susceptibility, as well as genes that are differentially expressed in all coral species in response to SCTLD infection. We find that SCTLD infection induces increased expression of rab7, an established marker of in situ degradation of dysfunctional Symbiodiniaceae, in all coral species accompanied by genus-level shifts in Symbiodiniaceae photosystem and metabolism gene expression. Overall, our results indicate that SCTLD infection induces symbiophagy across coral species and that the severity of disease is influenced by Symbiodiniaceae identity.https://doi.org/10.1038/s41467-023-38612-4 |
| spellingShingle | Kelsey M. Beavers Emily W. Van Buren Ashley M. Rossin Madison A. Emery Alex J. Veglia Carly E. Karrick Nicholas J. MacKnight Bradford A. Dimos Sonora S. Meiling Tyler B. Smith Amy Apprill Erinn M. Muller Daniel M. Holstein Adrienne M. S. Correa Marilyn E. Brandt Laura D. Mydlarz Stony coral tissue loss disease induces transcriptional signatures of in situ degradation of dysfunctional Symbiodiniaceae Nature Communications |
| title | Stony coral tissue loss disease induces transcriptional signatures of in situ degradation of dysfunctional Symbiodiniaceae |
| title_full | Stony coral tissue loss disease induces transcriptional signatures of in situ degradation of dysfunctional Symbiodiniaceae |
| title_fullStr | Stony coral tissue loss disease induces transcriptional signatures of in situ degradation of dysfunctional Symbiodiniaceae |
| title_full_unstemmed | Stony coral tissue loss disease induces transcriptional signatures of in situ degradation of dysfunctional Symbiodiniaceae |
| title_short | Stony coral tissue loss disease induces transcriptional signatures of in situ degradation of dysfunctional Symbiodiniaceae |
| title_sort | stony coral tissue loss disease induces transcriptional signatures of in situ degradation of dysfunctional symbiodiniaceae |
| url | https://doi.org/10.1038/s41467-023-38612-4 |
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