Rufinamide Use in Refractory Epilepsies
The drug rufinamide was approved in November 2008 by the US Food and Drug Administration for use in the adjunctive treatment of seizures associated with Lennox-Gastaut syndrome in patients older than 4 years. Lennox-Gastaut Syndrome is one of the most treatment-resistant epilepsies, and seizures req...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2015-08-01
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| Series: | Archives of Epilepsy |
| Subjects: | |
| Online Access: |
http://archepilepsy.org/archives/archive-detail/article-preview/rufinamide-use-in-refractory-epilepsies/55091
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| _version_ | 1797767376859561984 |
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| author | Abidin ERDAL Yasemin AYDEMİR F. Ezgi UÇAN TOKUÇ Gizem ÖZDEMİR Gülnihal KUTLU Fatma GENÇ Yasemin BİÇER GÖMCELİ |
| author_facet | Abidin ERDAL Yasemin AYDEMİR F. Ezgi UÇAN TOKUÇ Gizem ÖZDEMİR Gülnihal KUTLU Fatma GENÇ Yasemin BİÇER GÖMCELİ |
| author_sort | Abidin ERDAL |
| collection | DOAJ |
| description | The drug rufinamide was approved in November 2008 by the US Food and Drug Administration for use in the adjunctive treatment of seizures associated with Lennox-Gastaut syndrome in patients older than 4 years. Lennox-Gastaut Syndrome is one of the most treatment-resistant epilepsies, and seizures require a diversity of polytherapy. In recent years, a remarkable number of reports have been published on the effectiveness of rufinamide in childhood epileptic encephalopathy and epileptic spasms, tonic seizures, myoclonic-astatic epilepsy, Dravet syndrome, and refractory partial seizures dependent on migration abnormalities. This article discusses the efficiency of rufinamide as used in the treatment of five refractor epileptic cases at the Epilepsy Clinic established in Antalya Education and Research Hospital in August 2011. |
| first_indexed | 2024-03-12T20:37:50Z |
| format | Article |
| id | doaj.art-169cf2d2249d466290c5cce46f4a3617 |
| institution | Directory Open Access Journal |
| issn | 2792-0550 |
| language | English |
| last_indexed | 2024-03-12T20:37:50Z |
| publishDate | 2015-08-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Archives of Epilepsy |
| spelling | doaj.art-169cf2d2249d466290c5cce46f4a36172023-08-01T11:14:15ZengGalenos YayineviArchives of Epilepsy2792-05502015-08-01212818510.5505/epilepsi.2015.8554713049054Rufinamide Use in Refractory EpilepsiesAbidin ERDAL0Yasemin AYDEMİR1F. Ezgi UÇAN TOKUÇ2Gizem ÖZDEMİR3Gülnihal KUTLU4Fatma GENÇ5Yasemin BİÇER GÖMCELİ6 Antalya Education And Research Hospital, Department Of Neurology, Antalya, Turkey Antalya Education And Research Hospital, Department Of Neurology, Antalya, Turkey Antalya Education And Research Hospital, Department Of Neurology, Antalya, Turkey Antalya Education And Research Hospital, Department Of Neurology, Antalya, Turkey Department Of Neurology And Clinical Neurophysiology, Muğla Sıtkı Koçman University Medical School, Muğla, Turkey Antalya Education And Research Hospital, Department Of Neurology, Antalya, Turkey Antalya Education And Research Hospital, Department Of Neurology, Antalya, Turkey The drug rufinamide was approved in November 2008 by the US Food and Drug Administration for use in the adjunctive treatment of seizures associated with Lennox-Gastaut syndrome in patients older than 4 years. Lennox-Gastaut Syndrome is one of the most treatment-resistant epilepsies, and seizures require a diversity of polytherapy. In recent years, a remarkable number of reports have been published on the effectiveness of rufinamide in childhood epileptic encephalopathy and epileptic spasms, tonic seizures, myoclonic-astatic epilepsy, Dravet syndrome, and refractory partial seizures dependent on migration abnormalities. This article discusses the efficiency of rufinamide as used in the treatment of five refractor epileptic cases at the Epilepsy Clinic established in Antalya Education and Research Hospital in August 2011. http://archepilepsy.org/archives/archive-detail/article-preview/rufinamide-use-in-refractory-epilepsies/55091 dirençli epilepsilennox-gastaut sendromurufinamidsubakut sklerozan panensefalit |
| spellingShingle | Abidin ERDAL Yasemin AYDEMİR F. Ezgi UÇAN TOKUÇ Gizem ÖZDEMİR Gülnihal KUTLU Fatma GENÇ Yasemin BİÇER GÖMCELİ Rufinamide Use in Refractory Epilepsies Archives of Epilepsy dirençli epilepsi lennox-gastaut sendromu rufinamid subakut sklerozan panensefalit |
| title | Rufinamide Use in Refractory Epilepsies |
| title_full | Rufinamide Use in Refractory Epilepsies |
| title_fullStr | Rufinamide Use in Refractory Epilepsies |
| title_full_unstemmed | Rufinamide Use in Refractory Epilepsies |
| title_short | Rufinamide Use in Refractory Epilepsies |
| title_sort | rufinamide use in refractory epilepsies |
| topic | dirençli epilepsi lennox-gastaut sendromu rufinamid subakut sklerozan panensefalit |
| url |
http://archepilepsy.org/archives/archive-detail/article-preview/rufinamide-use-in-refractory-epilepsies/55091
|
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