Insulin Conformation Changes in Hybrid Alginate–Gelatin Hydrogel Particles

Insulin Conformation Changes in Hybrid Alginate–Gelatin Hydrogel Particles

There is a strong need to develop an insulin delivery system suitable for oral administration and preserving natural (α-helix) insulin conformation. In this work, we fabricated alginate–gelatin hydrogel beads for insulin encapsulation. Altering matrix composition and crosslinking agents has resulted...

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Bibliographic Details
Main Authors: Gulzhan Ye. Yerlan, Michael Shen, Bakyt B. Tyussyupova, Sagdat M. Tazhibayeva, Kuanyshbek Musabekov, Paul Takhistov
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Molecules
Subjects:
hydrogel particles
insulin
insulin fibrinogenesis
gelatin
alginate
Online Access:https://www.mdpi.com/1420-3049/29/6/1254

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