Secular Trends of Liver Cancer Mortality and Years of Life Lost in Wuhan, China 2010–2019
Background: Liver cancer has caused a heavy burden worldwide. This study aimed to estimate the trends in the mortality and years of life lost (YLL) due to liver cancer and decompose the total deaths into three contributors: population growth, population aging, and mortality change. Methods: Our stud...
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| Format: | Article |
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MDPI AG
2023-01-01
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| Series: | Current Oncology |
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| Online Access: | https://www.mdpi.com/1718-7729/30/1/71 |
| _version_ | 1797443944863236096 |
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| author | Yuanyuan Zhao Donghui Yang Yaqiong Yan Xiaoxia Zhang Niannian Yang Yan Guo Chuanhua Yu |
| author_facet | Yuanyuan Zhao Donghui Yang Yaqiong Yan Xiaoxia Zhang Niannian Yang Yan Guo Chuanhua Yu |
| author_sort | Yuanyuan Zhao |
| collection | DOAJ |
| description | Background: Liver cancer has caused a heavy burden worldwide. This study aimed to estimate the trends in the mortality and years of life lost (YLL) due to liver cancer and decompose the total deaths into three contributors: population growth, population aging, and mortality change. Methods: Our study used data from the cause-of-death surveillance system in Wuhan. The mortality and YLL rates were standardized according to the sixth national population census in China. This study calculated the estimated annual percentage change (EAPC) to estimate the trends in the age-standardized mortality rate (ASMR) and age-standardized YLL rate (ASYR). Meanwhile, a decomposition analysis was used to explore the effect of population growth, population aging, and age-specific mortality change on the change in liver cancer deaths. Results: The ASMR of liver cancer declined at an annual rate of 4.6% from 30.87 per 100,000 people in 2010 to 20.29 per 100,000 people in 2019, while the ASYR was at an annual rate of 5.6% from 969.35 per 100,000 people in 2010 to 581.82 per 100,000 people in 2019. Similar downward trends were seen in men and women. The decomposition analysis found that total deaths number changed by −12.42% from 2010 to 2019, of which population growth and population aging caused the total death numbers to increase by 9.75% and 21.15%, while the age-specific mortality change caused the total death numbers to decrease by 43.32%. Conclusion: Although the ASMR of liver cancer has declined in recent years in Wuhan, it still causes a heavy burden with the increasing population and rapid population aging and remains an essential public health issue. The government should take measures to reduce the burden of liver cancer, especially among men. |
| first_indexed | 2024-03-09T13:04:26Z |
| format | Article |
| id | doaj.art-169eacb703a146ab8519fa1576fe1645 |
| institution | Directory Open Access Journal |
| issn | 1198-0052 1718-7729 |
| language | English |
| last_indexed | 2024-03-09T13:04:26Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Current Oncology |
| spelling | doaj.art-169eacb703a146ab8519fa1576fe16452023-11-30T21:49:52ZengMDPI AGCurrent Oncology1198-00521718-77292023-01-0130193894810.3390/curroncol30010071Secular Trends of Liver Cancer Mortality and Years of Life Lost in Wuhan, China 2010–2019Yuanyuan Zhao0Donghui Yang1Yaqiong Yan2Xiaoxia Zhang3Niannian Yang4Yan Guo5Chuanhua Yu6Wuhan Center for Disease Control and Prevention, Wuhan 430024, ChinaDepartment of Epidemiology and Biostatistics, School of Public Health, Wuhan University, Wuhan 430072, ChinaWuhan Center for Disease Control and Prevention, Wuhan 430024, ChinaWuhan Center for Disease Control and Prevention, Wuhan 430024, ChinaWuhan Center for Disease Control and Prevention, Wuhan 430024, ChinaWuhan Center for Disease Control and Prevention, Wuhan 430024, ChinaDepartment of Epidemiology and Biostatistics, School of Public Health, Wuhan University, Wuhan 430072, ChinaBackground: Liver cancer has caused a heavy burden worldwide. This study aimed to estimate the trends in the mortality and years of life lost (YLL) due to liver cancer and decompose the total deaths into three contributors: population growth, population aging, and mortality change. Methods: Our study used data from the cause-of-death surveillance system in Wuhan. The mortality and YLL rates were standardized according to the sixth national population census in China. This study calculated the estimated annual percentage change (EAPC) to estimate the trends in the age-standardized mortality rate (ASMR) and age-standardized YLL rate (ASYR). Meanwhile, a decomposition analysis was used to explore the effect of population growth, population aging, and age-specific mortality change on the change in liver cancer deaths. Results: The ASMR of liver cancer declined at an annual rate of 4.6% from 30.87 per 100,000 people in 2010 to 20.29 per 100,000 people in 2019, while the ASYR was at an annual rate of 5.6% from 969.35 per 100,000 people in 2010 to 581.82 per 100,000 people in 2019. Similar downward trends were seen in men and women. The decomposition analysis found that total deaths number changed by −12.42% from 2010 to 2019, of which population growth and population aging caused the total death numbers to increase by 9.75% and 21.15%, while the age-specific mortality change caused the total death numbers to decrease by 43.32%. Conclusion: Although the ASMR of liver cancer has declined in recent years in Wuhan, it still causes a heavy burden with the increasing population and rapid population aging and remains an essential public health issue. The government should take measures to reduce the burden of liver cancer, especially among men.https://www.mdpi.com/1718-7729/30/1/71liver cancerdisease burdentrenddecompositionWuhan |
| spellingShingle | Yuanyuan Zhao Donghui Yang Yaqiong Yan Xiaoxia Zhang Niannian Yang Yan Guo Chuanhua Yu Secular Trends of Liver Cancer Mortality and Years of Life Lost in Wuhan, China 2010–2019 Current Oncology liver cancer disease burden trend decomposition Wuhan |
| title | Secular Trends of Liver Cancer Mortality and Years of Life Lost in Wuhan, China 2010–2019 |
| title_full | Secular Trends of Liver Cancer Mortality and Years of Life Lost in Wuhan, China 2010–2019 |
| title_fullStr | Secular Trends of Liver Cancer Mortality and Years of Life Lost in Wuhan, China 2010–2019 |
| title_full_unstemmed | Secular Trends of Liver Cancer Mortality and Years of Life Lost in Wuhan, China 2010–2019 |
| title_short | Secular Trends of Liver Cancer Mortality and Years of Life Lost in Wuhan, China 2010–2019 |
| title_sort | secular trends of liver cancer mortality and years of life lost in wuhan china 2010 2019 |
| topic | liver cancer disease burden trend decomposition Wuhan |
| url | https://www.mdpi.com/1718-7729/30/1/71 |
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